Protein Info for Dshi_0432 in Dinoroseobacter shibae DFL-12

Annotation: Arginine deiminase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02274: ADI
  • amino acids 37 to 406 (370 residues), 382.3 bits, E=2.6e-118

Best Hits

Swiss-Prot: 100% identical to ARCA_DINSH: Arginine deiminase (arcA) from Dinoroseobacter shibae (strain DSM 16493 / NCIMB 14021 / DFL 12)

KEGG orthology group: K01478, arginine deiminase [EC: 3.5.3.6] (inferred from 100% identity to dsh:Dshi_0432)

Predicted SEED Role

"Arginine deiminase (EC 3.5.3.6)" in subsystem Arginine Deiminase Pathway or Arginine and Ornithine Degradation (EC 3.5.3.6)

MetaCyc Pathways

• L-arginine degradation XIII (reductive Stickland reaction) (5/5 steps found)
• L-arginine degradation V (arginine deiminase pathway) (4/4 steps found)
• L-arginine degradation XIV (oxidative Stickland reaction) (2/6 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.6

Sequence Analysis Tools

See A8LN36 at UniProt or InterPro

Protein Sequence (409 amino acids)

>Dshi_0432 Arginine deiminase (RefSeq) (Dinoroseobacter shibae DFL-12)
MTAHKLGVHSETGTLRQVIICRPGLAHRRLTPENCEELLFDDVFWVKQAKQDHEAFGAAM
TQEGVEVLETGALLGETLEIPEARKWVLDHRISANDVGVGMRKDLRDWMDELPGTELATW
LIGGLTVGDVPFEATSMFGAYLGRHGFILPPLPNFLFTRDNSSWVYGGVTLNPMYWQARR
PETLLTAAIYRYHPKFAGKVHEIWADPLKNHGLATLEGGDVMPVGNGLVLVGMGERTSPQ
GVGLMAQALFGEGRATRVIACQMPKSRAAMHLDTVFTFCGDNIVTSFKEVADEMTCYDLH
PGEGDKPLDMRHDTRPMFEVVAEAMGFKKLNVVPTGGSDPFEQSREQWNDGNNVLALRPG
VVMGYDRNDDTNAALRAEGIKVIELPGAELGRGRGGSRCMSCPTIRDAV