Protein Info for Dshi_0362 in Dinoroseobacter shibae DFL-12

Annotation: peptidase M16 domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00675: Peptidase_M16" amino acids 39 to 176 (138 residues), 38.4 bits, see alignment E=1.2e-13 PF05193: Peptidase_M16_C" amino acids 188 to 360 (173 residues), 91.4 bits, see alignment E=6.8e-30

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_0362)

Predicted SEED Role

"Peptidase, M16 family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LMD4 at UniProt or InterPro

Protein Sequence (437 amino acids)

>Dshi_0362 peptidase M16 domain protein (RefSeq) (Dinoroseobacter shibae DFL-12)
MSRILGGFAALILWAVPAWAIVDIQEVTSPGGIEAWLVEDHSIPFTALEIRFEGGAALDP
EGKRGAAYFMSGLLEEGAGEYDARGYAARTEALAASFEFDISDDSLAISARFLTENRDEA
LEHLRLAIQEPRFDDEAIERVRAQILSVIASDAQDPNAIVGARFDALAFPDHPYGTPYEG
SAESVAGLTRDDLVASHRAILARDRIHVGAAGDITAEELGGVLDALLGALPETGAPLPED
TEVALTGGVTVVPFASPQSVARFGHEGLARDDPDFFPAFILNQIVGGGGFSSRLMQEVRV
ERGLTYGIGSYLLPLDDAALYIGQFSSDNTRIAEAIAVIREQWADIAANGVTAEELDEAK
VYLTGAYPLRFDGNGRIASILVGMQQDDLSIDYIPTRNDKVRAVTLEDIARVAARLLRPE
DLRFVVVGMPEGLEASN