Protein Info for Dshi_0335 in Dinoroseobacter shibae DFL-12

Annotation: pyridine nucleotide-disulphide oxidoreductase dimerisation region (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 PF07992: Pyr_redox_2" amino acids 8 to 317 (310 residues), 205.3 bits, see alignment E=5.1e-64 PF01134: GIDA" amino acids 8 to 67 (60 residues), 24.1 bits, see alignment E=6.2e-09 PF13738: Pyr_redox_3" amino acids 124 to 302 (179 residues), 49.4 bits, see alignment E=1.4e-16 PF00070: Pyr_redox" amino acids 172 to 246 (75 residues), 57.6 bits, see alignment E=5.3e-19 PF02852: Pyr_redox_dim" amino acids 338 to 445 (108 residues), 88 bits, see alignment E=1.7e-28

Best Hits

KEGG orthology group: K00520, mercuric reductase [EC: 1.16.1.1] (inferred from 100% identity to dsh:Dshi_0335)

Predicted SEED Role

"Mercuric ion reductase (EC 1.16.1.1)" in subsystem Mercuric reductase or Mercury resistance operon (EC 1.16.1.1)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.16.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LMA7 at UniProt or InterPro

Protein Sequence (470 amino acids)

>Dshi_0335 pyridine nucleotide-disulphide oxidoreductase dimerisation region (RefSeq) (Dinoroseobacter shibae DFL-12)
MTNRIETDICVIGAGSGGLSVAAGAVQMGARVVLIEGHLMGGDCLNFGCVPSKALIAAGK
QAHIVRAGGFGVAPAEPVIDYAAAKDHVRRVIDTIAPVDSQERFEGLGCTVIREYASFIS
ETELQAGDTVITARRFVIATGSRPFVPPIPGVEDVPYYTNETIFDLREKPEHLIIIGGGP
IGMEMAQAHVRLGCKVTVLEGAQALGKDDPELAAIALERLRGEGIEIIEGAQASNISGKG
GAITVETANGQSVTGTHLLMAVGRTPNLDKLNLEAAGVDYDRRGLKVDASLRTTNKRIYG
AGDVAGPLQFTHVAGYHAGILIRQLVLGLPAKTRDDHVPWATYTDPEIAQVGLTEAQARE
KYGAALEVARFEYDENDRAIASGKTTGLIKVMVVKGRPIGASIVGAEAGELIGLWAYAIA
NKHKMSAVANMIAPYPTLGEINKRAAGAYFSPRLFESALVKRIVRIVQKF