Protein Info for Dshi_0161 in Dinoroseobacter shibae DFL-12

Annotation: cobalt transporter, subunit CbtA (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 73 to 95 (23 residues), see Phobius details amino acids 107 to 125 (19 residues), see Phobius details amino acids 144 to 162 (19 residues), see Phobius details amino acids 169 to 188 (20 residues), see Phobius details amino acids 198 to 224 (27 residues), see Phobius details PF09490: CbtA" amino acids 4 to 224 (221 residues), 153 bits, see alignment E=6.4e-49

Best Hits

KEGG orthology group: None (inferred from 100% identity to dsh:Dshi_0161)

Predicted SEED Role

"Predicted cobalt transporter CbtA" in subsystem Coenzyme B12 biosynthesis or Transport of Nickel and Cobalt

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LKR7 at UniProt or InterPro

Protein Sequence (229 amino acids)

>Dshi_0161 cobalt transporter, subunit CbtA (RefSeq) (Dinoroseobacter shibae DFL-12)
MSMKLLTSAVFAGLAAGLIAALLQFSFVTSSLLEGELYEAGEKVHFAVDGTPQSPRGGAE
VDLAAEPVRYGLTVAFNIVTYTGFGLLLVALMALAETKKLTKITPRQGLIWGLAGFVAIQ
LAPAMGQPPVLPGSVGAEIGPRQAWWLATLLSAGLAMWLLAFGRGLWPWLAIPLLLVPQI
IGAPVLDTYFGVTPAELAASFAAMSLGYSAAGWAALGFFAAYFYSRQEA