Protein Info for Dshi_0035 in Dinoroseobacter shibae DFL-12

Annotation: Thioredoxin domain (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 PF00085: Thioredoxin" amino acids 19 to 120 (102 residues), 88.9 bits, see alignment E=4.1e-29 PF14559: TPR_19" amino acids 142 to 208 (67 residues), 45.7 bits, see alignment E=1.4e-15 PF14561: TPR_20" amino acids 213 to 302 (90 residues), 105.5 bits, see alignment E=3.1e-34

Best Hits

KEGG orthology group: K05838, putative thioredoxin (inferred from 100% identity to dsh:Dshi_0035)

Predicted SEED Role

"FIG000875: Thioredoxin domain-containing protein EC-YbbN"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A8LJV8 at UniProt or InterPro

Protein Sequence (303 amino acids)

>Dshi_0035 Thioredoxin domain (RefSeq) (Dinoroseobacter shibae DFL-12)
MLEFGQTGGGAPAAGDLVKDTTEATFMADVVDASQEIPVIVDFWAPWCGPCKTLGPALEA
EVTAAKGKVRMVKVNVDEAQMIAGQMRIQSIPTVYAFHKGQPVDGFQGAITPAEIKDFVS
RVAALGGDDGLGEAVEAAEAMLTEGAAVDAAQTFAAILGEEPENAAAYGGLVRAHLAMDE
LDKAEALIAAAPDAVAKSPELDAARAQLELARQAAQAGPVAELRAKVTADPDDHQARFDL
AQALYANGDTQAAVDELLDLFRRDRDWRDGAAKTQLFTIFDALKPEDPIALQGRRRLSSM
IFA