Protein Info for BT4355 in Bacteroides thetaiotaomicron VPI-5482

Annotation: RNA polymerase ECF-type sigma factor (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 191 TIGR02985: RNA polymerase sigma-70 factor, Bacteroides expansion family 1" amino acids 22 to 178 (157 residues), 165.1 bits, see alignment E=1.6e-52 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 23 to 175 (153 residues), 78.7 bits, see alignment E=3.9e-26 PF04542: Sigma70_r2" amino acids 27 to 88 (62 residues), 28.2 bits, see alignment E=1.9e-10 PF08281: Sigma70_r4_2" amino acids 123 to 174 (52 residues), 67.4 bits, see alignment E=1e-22 PF04545: Sigma70_r4" amino acids 128 to 175 (48 residues), 33.9 bits, see alignment E=2.8e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_4355)

Predicted SEED Role

"RNA polymerase ECF-type sigma factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q89ZM2 at UniProt or InterPro

Protein Sequence (191 amino acids)

>BT4355 RNA polymerase ECF-type sigma factor (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MEELRIKRNDLQLSEIQRGGLKAFETLFRQYYAVLCAYGHKYVDFHDAEEIVQDSLLWIW
ENRENLIIESSLSSYLFKMVHHKALNKLAHIDAIKRADTRFYEEMQEMIHDMDFYQIKEL
TKRIEDAVAALPESYRQAFVMHRFRDMSYKEIAETLEVSPKTVDYRIQQALKQLRIDLKD
YLPLLLPLLFP