Protein Info for BT4344 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein, putative DNA helicase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1605 PF13195: DUF4011" amino acids 385 to 556 (172 residues), 173 bits, see alignment E=1.6e-54 PF13086: AAA_11" amino acids 669 to 746 (78 residues), 37.1 bits, see alignment 1.1e-12 amino acids 1316 to 1359 (44 residues), 32.2 bits, see alignment (E = 3.4e-11) PF13087: AAA_12" amino acids 1388 to 1571 (184 residues), 57.5 bits, see alignment E=5e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_4344)

Predicted SEED Role

"Superfamily I DNA and RNA helicases and helicase subunits"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q89ZN3 at UniProt or InterPro

Protein Sequence (1605 amino acids)

>BT4344 conserved hypothetical protein, putative DNA helicase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MDGTLDKIRVQFDYLPLINFAMQQNKVSVIHQLSIENMTSEPFRNIQVQITAEPDFGSIT
PVMVEAIPANDSVCLQSFSLVLSANYFAQLTERMSGSLKIEIRSEAETIFTRTYPIDILA
YDQWGGINIFPEMLAAFITPNHAVLTPIIKRAAAILEQWTGTPSLDEYQSRNPDRVRKQM
AAIYTALTEQQIIYSTIPASFEEHGQRVRLTDSVLAQKLGTCLDMALLYASCLESIGLNA
LIVITKGHAFAGGWLVPETFPDPAIDDVSLLTKRTAEGIYDITLVETTCMNMGHNADFDN
AVKSANGKLSDPGSFILAIDVRRARHSGVRPIPQRVLNGQVWEIKEDEDMNRNTTHATPQ
SVNPYDLSGSETQTVLTKQLLWERRLLDLSLRNNLLNIRITKNTLQLIPANLACLEDALA
EGDEFRILHRPAEWENPAMEFGIYSSIPESDPIADFVNSELSQKRLRFYLPENDLGKALT
HLYRSSRTSIEENGANTLYLALGLLKWYETPSSERPRYAPILLLPVEIIRKSAAKGYVIR
SREEETMMNITLLEMLRQNFGISVPGLDPLPTDESGVNVKLIYSIIRHCIKNQRKWDVEE
QAILGIFSFNKFIMWNDIHNNAPKLTQNKIVSSLINGKIEWNAITEEMDASYMDRQLSPA
DIVLPIIADSSQLEAIYEAVHDKTFILHGPPGTGKSQTITNIIANALYKGKRVLFVAEKM
AALSVVQNRLAAIGLAPFCLEIHSNKTKKSTVISQLKETTEIIRRTPPEEFKKEAERLLK
LRTELNKYIEALHKEYPFGLSLYDAIIHYQSTDVEPCFDIPSSYLDDLDKDRFSHWEDAI
ESLVSTANACGHPHLHPLTGISIREYSSAIKEEASQTLATFIGLLTAIQSKLPVFSALLE
DTDIHPTRKDFDIITAIIRKILEIPELTPELLTTPLLNETLEEYRKVTKHGRKRDEIKAE
IENGFTKEVLKINAGPMLAEWNRVSAQWFLPRYFGQRKIKKAIRPYALQPVEPETVQPLL
HQVIRYQEELDFTDRYTAKLPSLFGRFGRDEEWDIIDQIIHEVSSLHSLLLSYSKDVAKT
SRIKQNLALQLTEGIRTFRDIHSHSLNELHQLADTLTATEQRLSTTLGITVETLYTNSAD
WIGIALQQAATWKENLDKLKDWYQWLQSYNKLNELGIGFIAEEYKEKNIPTDLLTSSFCK
SFYQAVIHYIIAKEPTLELFNGKIFNDIIAKYKQVSANFEDITKKELFARLASNIPSFTH
EAIQSSEVGILQKNIRNNARGISIRKLFDQIPTLLSRMCPCMLMSPISVAQYIDTDADKF
DLIVFDEASQMPTYEAVGAIARGKNVVIVGDPKQMPPTSFFSVNTIDEDNIEMEDLESIL
DDCLALSIPSKYLLWHYRSKHESLIAFSNSEYYDNKLMTFPSPDNIESKVRMVAVDGYYD
KGKSRQNQAEAQAVVDEIARRLRSEELRKKSVGVVTFSVVQQALIEDLLSDLFIFHPELE
TFALECEEPLFIKNLENVQGDERDVILFSVGYGPDAEGRVSMNFGPLNRAGGERRLNVAV
SRARYEMIIFSTLRSDMIDLNRTSSIGVAGLKRFLEYAEKGPSAY