Protein Info for BT3854 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1012 TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 7 to 1012 (1006 residues), 930.3 bits, see alignment E=1.8e-283 PF13620: CarboxypepD_reg" amino acids 8 to 67 (60 residues), 36.6 bits, see alignment 7.2e-13 PF13715: CarbopepD_reg_2" amino acids 8 to 88 (81 residues), 52.7 bits, see alignment E=5.6e-18 PF07715: Plug" amino acids 96 to 199 (104 residues), 63.7 bits, see alignment E=3.2e-21 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 176 to 205 (30 residues), 50.5 bits, see alignment (E = 1.3e-17)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_3854)

MetaCyc: 100% identical to TonB-dependent manno-oligosaccharide transporter monomer (Bacteroides thetaiotaomicron)
TRANS-RXN-1547

Predicted SEED Role

No annotation

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A117 at UniProt or InterPro

Protein Sequence (1012 amino acids)

>BT3854 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MAQENLKISGQVTDNKGEAIIGASVKVLKTGTGTISDMDGKFTIQVPVGAELEIGYVGYN
PKRVKVVNKNFVTVVLEENVVALGDVVVVGYGIQKKESLTGAIGNLKVDDIVKTKAPSLA
QAIQGKVAGLRIRQENGEPGKFSSNINVRGFGTPLFVIDGVVRDGSSEFQRLNPEDIESI
SFLKDATASIYGMNSANGAVIVTTKKGATGKPRITLNANVGITSPTNVPEMANARQYMTM
RNEAEINAGRPAYITKDELTKWQQGAPGYESVDLYDAVFNKHATQFQTTLSLEGGTDKVS
YYGSFGYATDNSLLKNNALTYDKYTFRSNVSLKITKDLTASINLGGRYDTTNRPWFPFYD
IFKSTRVNPPTTSIYANDNPDYYNNFSYVPNPAAMIDADYTGSAKERNKNLQTQFALEYN
IPYVKGLKVKGTFIYDYNNYGYKATRKGFKTYTYGEYTGEYTAADANYPALLQDNRRESE
RVDMQFQTNYNRTFGNHTIGATYVFERREEKANWMNGERKFDFFTIGELDNARESEPEVS
GSSEHQAYLSHIGRLTYDYKGKYLAELACRYDGSYRYAPGSRWAFFPSASVGWRISEESF
IKDNFKFVDNLKLRFSAGRSGQDAGDPFQYFSGYTLNSGGYVFSQGNYTNGVASPVMINK
NLTWIKVNMYNIGIDFSIFNRLIAVEFDIYQRDRSGLLADRYGSLPNTFGSKLPQENLNG
DRTRGIEFTLTHTNKIGDFHYSVSGNFNLARTQRRYIESGPYKSSMERWRNQSSNRWGDF
IWGYQTDGRFQNFDEINTYPIQNGDNGNSKELPGDYILKDVNGDGVVNDLDKTPLFWSGS
PLIHYGFNVEASWKNFDFYALFQGSALYTVQFDEVYAKMLCFKGGNTPEYFYDRWHLSDP
YDANSEWIPGEWPAIRLEQDMGSFYTRDSQIWRKNASYLRLKTIEIGYTFSPRLMHKLGI
GSLRIYANGNNLFTVCDPFVKAFDPEKIEGDYSAGLNYPLNKSFNFGLTLNF