Protein Info for BT3835 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative GTP-binding protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 TIGR00231: small GTP-binding protein domain" amino acids 5 to 162 (158 residues), 83.5 bits, see alignment E=1.4e-27 TIGR00436: GTP-binding protein Era" amino acids 5 to 273 (269 residues), 262.4 bits, see alignment E=4.6e-82 PF01926: MMR_HSR1" amino acids 7 to 120 (114 residues), 83.9 bits, see alignment E=4e-27 PF02421: FeoB_N" amino acids 7 to 162 (156 residues), 60.8 bits, see alignment E=5.2e-20 PF10662: PduV-EutP" amino acids 9 to 164 (156 residues), 35.3 bits, see alignment E=4.5e-12 PF00009: GTP_EFTU" amino acids 17 to 168 (152 residues), 39.8 bits, see alignment E=1.7e-13 PF02492: cobW" amino acids 46 to 146 (101 residues), 24.9 bits, see alignment E=6.5e-09 PF07650: KH_2" amino acids 203 to 279 (77 residues), 74.7 bits, see alignment E=1.9e-24

Best Hits

Swiss-Prot: 44% identical to ERA_STAS1: GTPase Era (era) from Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)

KEGG orthology group: K03595, GTP-binding protein Era (inferred from 100% identity to bth:BT_3835)

Predicted SEED Role

"GTP-binding protein Era" in subsystem Bacterial Cell Division or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A136 at UniProt or InterPro

Protein Sequence (293 amino acids)

>BT3835 putative GTP-binding protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MHKAGFVNIVGNPNVGKSTLMNALVGERISIATFKAQTTRHRIMGIYNTDDMQIVFSDTP
GVLKPNYKLQESMLNFSTSALTDADVLLYVTDVVETPDKNNEFMGKVRQMTVPVLLLINK
IDLTDQEKLIKLVEEWKELLPQAEIIPISAASKFNVDYVMKRIQELLPDSPPYFGKDQWT
DKPARFFVNEIIREKILLYYDKEIPYSVEVVVEEFKEEAKKIHIRAVIYVERDSQKGIII
GKQGKALKKVATEARRELERFFGKTIFLETYVKVDKDWRSSDKELRNFGYQLD