Protein Info for BT3552 in Bacteroides thetaiotaomicron VPI-5482

Annotation: peptide chain release factor RF-2 (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 PF03462: PCRF" amino acids 3 to 162 (160 residues), 159.6 bits, see alignment E=8.3e-51 PF00472: RF-1" amino acids 171 to 287 (117 residues), 103.2 bits, see alignment E=8.8e-34

Best Hits

KEGG orthology group: K02836, peptide chain release factor 2 (inferred from 100% identity to bth:BT_3552)

Predicted SEED Role

"Peptide chain release factor 2; programmed frameshift-containing"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A1V6 at UniProt or InterPro

Protein Sequence (319 amino acids)

>BT3552 peptide chain release factor RF-2 (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKLVKDLQKWIDGYNEVKTLADELELSFDFYKEELVTEGDVDAAYAKASEAVEALELKNM
LRDEADQMACVLKINSGAGGTESQDWASMLMRMYLRYAETNGYKATIANLQEGDEAGIKT
CTINIEGDFAYGYLKGENGVHRLVRVSPYNAQGKRMTSFASVFVTPLVDDSIEVNILPAC
ISWDTFRSGGAGGQNVNKVESGVRLRYQYKDPYTGEEEEILIENTETRDQPKNRENAMRQ
LRSILYDKELQHRMAEQAKVEAGKKKIEWGSQIRSYVFDDRRVKDHRTNYQTSDVNGVMD
GKIEEFIKAYLMEFSSQES