Protein Info for BT3418 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative thiol:disulfide interchange protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 823 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF08534: Redoxin" amino acids 694 to 800 (107 residues), 27.3 bits, see alignment E=4.5e-10 PF13905: Thioredoxin_8" amino acids 696 to 792 (97 residues), 36.7 bits, see alignment E=6.6e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_3418)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A288 at UniProt or InterPro

Protein Sequence (823 amino acids)

>BT3418 putative thiol:disulfide interchange protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKTILLCMMLMLSGMLTAQTVDNPPFKARSGSIGNITRIERTPDGTRVYIHAIFRPHWWI
KEEGDSYLEDAATGKKYQFKSAEGIELNKEVYMPDSGEMDYVLVFEALPEETQVIHLLSP
SDTEGNTYDISLVPSSGKNVSPLAAIKGNWFKADDLNAWEYGIYDSVTIMDNRIFTNENI
RKKGKRVEITVKDKRNGDIRTLLVTPQKDGSCQIQVNGEKNQLYTRQRGATKTIAADTGF
QQFFHTDTTCLQGYIDGYDRRLGFDTGLIYLSNHITRQDYPTVIQIDEDGSFLCKFVIKH
PVEQSVTLDNNWIPFYIEPGQTLTMYIDWEALLARSRARDYYFPIKNTAYMGPSASLSYL
LKEFKSLIPYRYDDLSNARNKLTPSQYQEHMKPIVARWEHTADSLIQICRPSAKAARLIK
NKADLQAGGLFFDFLMSRDYYAKQDTANQALKVKEEDSYYDFLKKMPLNDETVLADANAS
SFINRFEYMDAFRTAYNYHAPKAKDTISYTYPEESLLAFLKERGVKLNAEQEAIRLKQEK
LAGTTVRIPLKELQEENDKVTGLYEKEEKLVLEYIDKQYKNKQSEQDMDRNFISMEQKTG
HKKDSILARLYDVPDPLLWQIAKVRNLGFSLQNIKTRSIAREYVDSIKQKLTHPQLAEEA
EYLFAKTHPKEKVNSYQLPEGKATDVFRNIIKNHPGKVLFVDFWATTCGPCRAGIEATAD
LRKKYKDHPEFEFIYITGQKDSPAGAYKQYVEKNLKGEASYYVTDSEFNYLRQLFRFNGI
PHYELVLKDGSISKEKLGTHRIRKYLEEHFPVSGSAGQGENDQ