Protein Info for BT3399 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative zinc protease (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 232 transmembrane" amino acids 176 to 190 (15 residues), see Phobius details PF01863: YgjP-like" amino acids 23 to 227 (205 residues), 161.5 bits, see alignment E=1.4e-51

Best Hits

KEGG orthology group: K07043, (no description) (inferred from 100% identity to bth:BT_3399)

Predicted SEED Role

"Putative predicted metal-dependent hydrolase" in subsystem Restriction-Modification System

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A2A6 at UniProt or InterPro

Protein Sequence (232 amino acids)

>BT3399 putative zinc protease (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MDTVIEDDELGSLIVRVNPRARSLVFRTKSDAVYVSVPPGTTTKEVKRAIENLRSKLLLS
RQKVARPLIDLDYKIDAEHFKLSLILGEKEQFLANSRLGVMQIVCPPQADFTDENLQNWL
RKVIEESLRRNAKSILPPRLEHLSAQCGLSYASVKINSSQGRWGSCSARKNINLSYYLVL
LPSHLIDYVLLHELCHTREMNHGERFWDLLNRFTDGKALALRKELKKYRTEI