Protein Info for BT2862 in Bacteroides thetaiotaomicron VPI-5482

Annotation: tyrosine-protein kinase ptk (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 787 transmembrane" amino acids 12 to 39 (28 residues), see Phobius details amino acids 488 to 509 (22 residues), see Phobius details PF13807: GNVR" amino acids 429 to 504 (76 residues), 34 bits, see alignment E=5.6e-12 TIGR01007: capsular exopolysaccharide family" amino acids 556 to 763 (208 residues), 140.7 bits, see alignment E=2.3e-45 PF13614: AAA_31" amino acids 576 to 697 (122 residues), 42.9 bits, see alignment E=1.3e-14 PF01656: CbiA" amino acids 578 to 615 (38 residues), 27.9 bits, see alignment 5e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2862)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A3U2 at UniProt or InterPro

Protein Sequence (787 amino acids)

>BT2862 tyrosine-protein kinase ptk (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MALTEEEKSINIVDLFIYLIAHWKWFVLSILLFGGYFWYSYCETPFVYSRTAIVMIKTPA
NSRSAMQLNNADFIGQVNVASEILQFKSKELMRKVIDRLHADVSYMVRDGLRPRELYTDS
PVRVAFLEAGLDEVCSLSVIPKNKQQVELADFSLDELEQRKTVNLNDTVDTPLGKLIVFT
AENYSESYFDRPIKVTSKSREGMVAFWLSNLTIRQMSGDAALLSMTMNDLSPTRAADILD
MLITVYNEEAIKDKNRISVNTAEFIKERLQIIEHELGSVETDIEDLKRANNGVDINTVAG
MYIQDSRQYESSIKELDTQLQLVSFIKQYLQDSNKDDELIPSNIGLSDLSIESQISRYNE
TLLRRNRLVSGSSSNNPVVQELNRIMQTMKQNIYMAVDNLSKSLRLKKQDYMRQESHVRQ
KVQAVPGKQREMLSIERQQKVKESLYIFLLNKREENALSQAMVDNNARILDPVSGSNLPI
SPNKYKKMILGVGCGIIVPSVILLLILMLDTRVHNRKEVEAVVSAPFLADIPQTAKASVD
AHEVVVRARGLDPLSEAFRILRTNLGFMLSQAQDHKIITLTSFNIGAGKTFVSVNLAASL
VQTKKKVLILDLDLRKGKMSEMAHSKHVKGVAHYLSNPSIVVDDLILRDAFGEGLDLIPI
GVIAPNPTELLLSRRLDELMDRLRELYDYIIVDNVPIGLVADASVVNRISDLTLFIVRVG
KIDRRQLPELERLYQEHKLTNMAVVLNGTKKGSSGYGYGYGYGQGYGYKNAEKKKGLFGR
KKKKSRK