Protein Info for BT2813 in Bacteroides thetaiotaomicron VPI-5482

Annotation: sodium-dependent multivitamin transporter (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 489 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 40 to 62 (23 residues), see Phobius details amino acids 74 to 92 (19 residues), see Phobius details amino acids 117 to 139 (23 residues), see Phobius details amino acids 149 to 167 (19 residues), see Phobius details amino acids 179 to 197 (19 residues), see Phobius details amino acids 228 to 247 (20 residues), see Phobius details amino acids 268 to 293 (26 residues), see Phobius details amino acids 323 to 350 (28 residues), see Phobius details amino acids 370 to 392 (23 residues), see Phobius details amino acids 398 to 419 (22 residues), see Phobius details amino acids 428 to 449 (22 residues), see Phobius details amino acids 461 to 482 (22 residues), see Phobius details TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 33 to 435 (403 residues), 222.8 bits, see alignment E=4.3e-70 PF00474: SSF" amino acids 35 to 435 (401 residues), 152.2 bits, see alignment E=1e-48

Best Hits

KEGG orthology group: K03307, solute:Na+ symporter, SSS family (inferred from 100% identity to bth:BT_2813)

Predicted SEED Role

"Predicted sialic acid transporter" in subsystem Sialic Acid Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A3Z1 at UniProt or InterPro

Protein Sequence (489 amino acids)

>BT2813 sodium-dependent multivitamin transporter (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MSILDIIIFLFFTGGVVVFGCSFFNKKRSSEEFTSAGRSLPGWVVGMSIFATYVSSISYL
AYPGKAYMSDWNAFVFSLSIPIASYFAAKYFVPFYRSIGSVSAYSFLEERFGPWARVYAS
SCYLLTQVARMGSILYLLALPMNALLGWDIKMIIAVTSVAIIAYSMLGGLKAVIWTEAIQ
GFILIGGAIACLCVLMFKMPEGPAQVFQIAITDQKFSLGSFGSSLTESTFWVCLIYGIFI
NLQNYGIDQNYVQRYLTAKSDKQAKFSALFGGYLFIPVSAVFFMIGTALYAYYKTFPELL
PAGVEGDAVFPYFIVHALPTGLTGLLIASIFAAGMSTVATSITSSATIILTDYYARYINK
RPTEKQSVRALYVSNVLIGIIGIFVALAFLNVESALDAWWALSSIFSGGMLGLFLLGYIS
KKARNVDAVLGVICGIIVVVWMSLSPIFFKDGFMSEYASPFHANLTIVFGTIVIFLAGFL
SMRLLKTKK