Protein Info for BT2809 in Bacteroides thetaiotaomicron VPI-5482

Updated annotation (from data): D-ribose transporter
Rationale: Specifically important in carbon source D-Ribose. It belongs to a family of sugar transporters. It probably moves D-ribose through the inner membrane.
Original annotation: putative integral membrane protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 39 to 60 (22 residues), see Phobius details amino acids 78 to 98 (21 residues), see Phobius details amino acids 106 to 129 (24 residues), see Phobius details amino acids 136 to 157 (22 residues), see Phobius details amino acids 170 to 188 (19 residues), see Phobius details amino acids 208 to 229 (22 residues), see Phobius details amino acids 251 to 273 (23 residues), see Phobius details amino acids 279 to 300 (22 residues), see Phobius details amino acids 312 to 332 (21 residues), see Phobius details PF06800: Sugar_transport" amino acids 15 to 327 (313 residues), 36.7 bits, see alignment E=5e-13 PF07168: Ureide_permease" amino acids 41 to 160 (120 residues), 31.1 bits, see alignment E=1.7e-11 amino acids 166 to 329 (164 residues), 61.6 bits, see alignment E=8.7e-21 PF07857: TMEM144" amino acids 169 to 331 (163 residues), 38.6 bits, see alignment E=9.9e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2809)

Predicted SEED Role

"FIG00761799: membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A3Z5 at UniProt or InterPro

Protein Sequence (334 amino acids)

>BT2809 D-ribose transporter (Bacteroides thetaiotaomicron VPI-5482)
MYIVNSYTLAIIFCFITMICWGSWGNTQKLASKNWRYELYYWDYTIGILLFALLLVFTLG
SFGDSGRGFLEDIQQVEAAYIASALIGGAIFNASNILLSASVSIAGMAVAFPLGVGLALV
LGVFINYFSSPKGDPFWLFTGVVLIVIAIICNGIAAGKNQKAGTNNSKKGIILAAIAGIL
MSFFYRFVAAAMDLNNFESPTTGMATPYTAFFIFAIGIFLSNFLFNTLVMKRPFVGLPVT
YKEYFAGKASTHMVGILGGCIWGLGTALSYIAAGKAGAAISYALGQGAPMIAALWGVFIW
KEFTGSSKATNRLLGVMFILFILGLTFIVISGGS