Protein Info for BT2726 in Bacteroides thetaiotaomicron VPI-5482

Annotation: 50S ribosomal protein L4 (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 TIGR03953: 50S ribosomal protein uL4" amino acids 17 to 204 (188 residues), 234.3 bits, see alignment E=3.4e-74 PF00573: Ribosomal_L4" amino acids 17 to 204 (188 residues), 225.5 bits, see alignment E=2.3e-71

Best Hits

Swiss-Prot: 100% identical to RL4_BACTN: 50S ribosomal protein L4 (rplD) from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

KEGG orthology group: K02926, large subunit ribosomal protein L4 (inferred from 100% identity to bth:BT_2726)

Predicted SEED Role

"LSU ribosomal protein L4p (L1e)" in subsystem Ribosome LSU bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A477 at UniProt or InterPro

Protein Sequence (208 amino acids)

>BT2726 50S ribosomal protein L4 (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MEVNVYNIKGEDTGRKVTLNESIFGIEPNDHAIYLDVKQFMANQRQGTHKSKERSEISGS
TRKIGRQKGGGGARRGDMNSPVLVGGARVFGPKPRDYFFKLNKKVKTLARKSALSYKVQN
NALIVVEDFVFEAPKTKDFVAMTKNLKVSDKKLLVILPEANKNVYLSARNIEGANVQTVS
GLNTYRVLNAGVVVLTENSLKAIDNILI