Protein Info for BT2362 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1028 signal peptide" amino acids 1 to 45 (45 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 48 to 1028 (981 residues), 909.3 bits, see alignment E=3.9e-277 PF13715: CarbopepD_reg_2" amino acids 53 to 130 (78 residues), 54.2 bits, see alignment 1.2e-18 PF07715: Plug" amino acids 137 to 243 (107 residues), 68 bits, see alignment E=9.9e-23 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 219 to 249 (31 residues), 62.3 bits, see alignment (E = 2.8e-21)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_2362)

Predicted SEED Role

"SusC, outer membrane protein involved in starch binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A580 at UniProt or InterPro

Protein Sequence (1028 amino acids)

>BT2362 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKSFSDKTNIGTYVTLKTVYMIRFYLLLLLTGGILVIGATQVYAQQSRTISSVVKNSQGE
TIIGANIVEKGTNNGTITNVDGLFTLRVSPNAVLKVSYMGYIEQEVSTRNKSKLEITMVE
DARLIDEVVVVGYGSVKKRDLTGAVTSVKSAEVLAAPTSNVMEALQGKIPGMDITKTSGQ
VGGEVSILLRGSRSIYGNNEPLFIIDGIPGSYSQVNPSDIESVDVLKDASSTAIYGSAGA
NGVVIITTKRGKEGKATINFDAYYGFSGSPNYKHGMTQDEWVTYQKEAYRYKNGDFPSDM
SALLGKQAFTDAYNAGKWIDWVDEVSGNTATTQKYSLSVSSGTEKTRIFASTSYNREEGL
LSNENLNRYSLRLNIDQQLFSWAKVGFTSNLVYRDLNSGVKNTFTRSLSAFPLGDAYDEE
GKINHEYITGQYSPMGDFIENQYANNTRSTYLNMSGYVELTPLKDFTFTSRINGTLNHSR
RGQYWGNQCNANRPSYAGSPHASITNDNAWNYTWENILAYSTTLAKAHTVGGSLITSWNK
NQSESNMAAASGQMVDQWSFWRLTSGSSPHVESDFAQTQKMSFAFRLNYSYKSKYLFNFS
TRWDGVSQFSAGHKWDAFPAGAIAWRISDEAFMEKTRSWLDNLKLRVSYGITGNSGGTDA
YSTTTQAYVYSASGVSVNGKIVPFTQYSETYGSADLGWEKSYNWNIGLDFGILNSRIDGS
IEWFRTTTKGLLFKRILPITSGLTGWGSPLSIWQNIAQTSNQGVEVILNSHNIQHKDFTW
NTTLSATWSKEKIDKLPDGDLISENLFTGEPIHAIYGYKYAGIWGSDTPKETLDAYGVNP
GFIKIETVDKNGDGGVHKYSTDDRQILGHTNPDWIIGLNNSFTYKNFDLSVFAMARYGQT
INSDLLGYYTAEQSVTKNQLAGVDYWTEDNQGAYFPRPGTGDEQKTVYPSLRVHDGSFIK
IKNITLGYTLPANISRKVLMEKCRIYATAYNPFIFVKDKQLKDTDPETNGSDAFPTYRQF
VFGVNLTF