Protein Info for BT2254 in Bacteroides thetaiotaomicron VPI-5482
Annotation: putative pectate lyase (NCBI ptt file)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 100% identity to bth:BT_2254)Predicted SEED Role
"rhamnogalacturonan acetylesterase" in subsystem L-rhamnose utilization
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q8A5I5 at UniProt or InterPro
Protein Sequence (364 amino acids)
>BT2254 putative pectate lyase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482) MRQTAFFFLLLFIQTGISAQATDYRKQQNYKEWVHLAPKFDDAFFRTEEAQRIGDNVLLY QQVTGGWPKNIYMPAELTEQEYAKARNAKEDVNQSTIDNNATTTEIQYLARLYQATQKEK YKEGVLKGIQYLLKAQYDNGGWPQFYPRPTGYYVQITYNDNAMVRVMQQLREIYEKQSPY TFIPDETCQQARKAFDKGIECILRTQVRQNGELTVWCAQHDRITLEPCKARAYELPSLSG QESDNIVLLLMSLPHPSEKVIESIESAVKWFKKSEIKGVQKEYFTNSDGKRDYRMIPCED CPVLWARFYELDTNRPFFSDRDGIKKYDISEIGHERRNGYSWYNKDGNKVLAKYEKWKKE LNRK