Protein Info for BT1650 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative teichoic acid biosynthesis protein F (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 385 transmembrane" amino acids 9 to 29 (21 residues), see Phobius details amino acids 72 to 91 (20 residues), see Phobius details PF04464: Glyphos_transf" amino acids 32 to 384 (353 residues), 150.1 bits, see alignment E=4.2e-48

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_1650)

Predicted SEED Role

"CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase (EC 2.7.8.12)" in subsystem Teichoic and lipoteichoic acids biosynthesis (EC 2.7.8.12)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.12

Use Curated BLAST to search for 2.7.8.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A775 at UniProt or InterPro

Protein Sequence (385 amino acids)

>BT1650 putative teichoic acid biosynthesis protein F (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MMLVIKHLLGYFILLVSYVFPRISTIWVFGGENNAKYLYYKLNEKAADINCIWISKSKEE
VAQVCSLKYKAFYLWSLKGLFYSLIAGRYIYTFSVSDINPWTIGWTKRVNLWHGVGIKNV
EFKCKLGPLAKKYNPNSLKSRFLYPYLFFRPHLFLSTSPLMTKHFTECFRISEDRCIEAM
YPRNEILLWAHDQIEEFLKRYNKEQELDVIEDCASYSYVYIYMPTWREDKRNILEIIDFD
RLNQLCIKNNNLFLFRLHPNTEINLDMLVSYSNLRIIDSSCDIYPILPFTDVLITDYSSI
YYDYMLIPNKQILLFPFDEEEYCTFNRDLAFDYKIYTPGIRIYSFEALLEIVESKKNLNI
KEIKVIKKLFWKGRNESIIDRIINL