Protein Info for BT1533 in Bacteroides thetaiotaomicron VPI-5482

Annotation: conserved hypothetical protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 291 to 311 (21 residues), see Phobius details amino acids 344 to 369 (26 residues), see Phobius details amino acids 390 to 412 (23 residues), see Phobius details PF12704: MacB_PCD" amino acids 24 to 246 (223 residues), 72.8 bits, see alignment E=5e-24 PF02687: FtsX" amino acids 293 to 422 (130 residues), 60.6 bits, see alignment E=1.6e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_1533)

Predicted SEED Role

"Macrolide-specific ABC-type efflux carrier (TC 3.A.1.122.1)" (TC 3.A.1.122.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8A7J1 at UniProt or InterPro

Protein Sequence (429 amino acids)

>BT1533 conserved hypothetical protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MIKLYFKQAFHLLKENKLLSSISIIGTALAIAMIMVIVITLRATIAPFAPESYRDRMLIF
RYAGFQYKTNENWQSNGPVSYKTAKACFKEMAAPEAVTITSSFSETMLAAKPAGEKVSCS
VLQVDDDFWKVFKFDFLSGYPFDKATFDAGATKAVISEDIARQLFGTSDVVGKTFLLNHS
AYMICGVVRPVSKLARYAYAQIWIPLSSTDAFTASWGEYGIMGMVSVYILAKSQDDFPAI
RMEAERLRDRYMEGYPDYELLYRDQPDTYFVAAQRYSANNPPAVKQAVRQYIITLIILLI
VPAVNLSGLTLSRMRKRLSEIGVRKAFGAPRRELMIQVLSENMLYSLLGGVLGLILSYGA
TFFLGSMLFSIDFMGNGVTDLRTMCMDLLFDPVVFLLAFFACFALNLLSAAIPAWRVTRT
NIVDAINER