Protein Info for BT0560 in Bacteroides thetaiotaomicron VPI-5482

Annotation: outer membrane efflux protein (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 409 PF02321: OEP" amino acids 21 to 207 (187 residues), 49.7 bits, see alignment E=1.8e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0560)

Predicted SEED Role

"Type I secretion system, outer membrane component LapE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8AAA5 at UniProt or InterPro

Protein Sequence (409 amino acids)

>BT0560 outer membrane efflux protein (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MPGMYGQTGHITLEECQQKTQDNYPLVRQYDLVEKTKEYNLENAARGYLPQFALSAKASY
QSDVTELPIAIPGVDIKGMAKDQYQVMLELQQQIWDGGGIRMQKKKATAEAEIDREKLNV
DMYALNGRVNDLYFGILMLDEQLAQNALLQDELGRNFRQITAYVENGIANQADLDAVKVE
QLNTRQKRVELTSSRMAYLKMLSLLMGEVLSPETVLEKPVPQNELSAVSEIRRPELSWFD
AQGAGLQVQEKALNVRHLPHFGLFVQGAYGNPGLNMLKNEFSPYYIAGVRLSWNFGSLYT
LKNDRRVIENKRQQLDSNRDVFLFNTRLEMTQQDQSVRSLEKQMQDDDEIIRLRTNIRRA
AEAKVANGTLTVTEMLRELTNESLARQAKAMHEIQRLMGIYQLKYTTNH