Protein Info for BT0482 in Bacteroides thetaiotaomicron VPI-5482

Annotation: tyrosine-protein kinase ptk (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 812 transmembrane" amino acids 28 to 49 (22 residues), see Phobius details amino acids 510 to 531 (22 residues), see Phobius details PF02706: Wzz" amino acids 16 to 112 (97 residues), 34.4 bits, see alignment E=6.7e-12 PF13807: GNVR" amino acids 453 to 527 (75 residues), 47.7 bits, see alignment E=3.5e-16 TIGR01007: capsular exopolysaccharide family" amino acids 580 to 786 (207 residues), 165.7 bits, see alignment E=5.2e-53 PF10609: ParA" amino acids 597 to 652 (56 residues), 28.1 bits, see alignment 4e-10 PF13614: AAA_31" amino acids 598 to 728 (131 residues), 32.8 bits, see alignment E=1.9e-11 PF01656: CbiA" amino acids 600 to 642 (43 residues), 27 bits, see alignment 1.1e-09

Best Hits

KEGG orthology group: None (inferred from 97% identity to bth:BT_0482)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8AAI2 at UniProt or InterPro

Protein Sequence (812 amino acids)

>BT0482 tyrosine-protein kinase ptk (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MKEEIVNERQCETEDEKIDIQQLLFKYIIHWPWFVGAVLVCLIGAWIYLRMATPVYNISA
TVLIKDDKKGGNTGSMVGLEELGLSGLISSSQNIDNELEVLRSKTLVKEVINLLNLYVSY
TDEDGFPSKNMYKTSPVLVSLTPQEAEKLTDPMVVEMALYGEGGLEVNVTVGDKEYQKHF
EKLPAVFPMDEGTLAFFQSPDSLSLKKDTMEASSNIRHITAKIKSPMKVARAYCENLKIE
PTSKTTSVAVISLKNSSLQRGQDFINQLLEMYNRNTNNDKNEIAQKTAEFIDERINIISK
ELGSTEANLENFKRNAGITDLTSEAQIALTGNAEYEKKRVENRTQISLIEDLRKYIRGNE
YEVLPGNIGLQDPGLVATIERYNEMLVERKRLLRTSTENNPTIINLDTSIRAMKSNVQAT
LDGSLKGLLITKADLEREASRFSRRISDAPGQERQFVSIARQQEIKAGLYLMLLQKREEN
AIALAATANNAKIIDEAIADDIPVSPKRRMIYLIALVLGIGIPVGIIYLIGLTKFKLEGR
ADVEKLTTIPIVGDIPLTDEKNEKDGSIAVFENQNNLMSETFRNIRTNLQFMLQNDKKVI
LVTSTVSGEGKSFISANLAISLSLLGKKVVIVGLDIRKPGLNKVFRLSTKEKGITLYLAN
PETDLMSLVQPSDINQNLYILPGGTVPPNPTELLARDGLDKAIEILKKNFDYVILDTAPV
GMVTDTLLIGRVADLSVYVCRADYTHKVEYTLINELAEEKKLPNLCTVINGVDLKRRKYG
YYYGYGKYGKYYGYGKRYGYGYGYGQEKGAKS