Protein Info for BT0386 in Bacteroides thetaiotaomicron VPI-5482

Annotation: putative F420H2-dehydrogenase (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 397 PF13187: Fer4_9" amino acids 12 to 61 (50 residues), 31.2 bits, see alignment 5.4e-11 PF04422: FrhB_FdhB_N" amino acids 73 to 141 (69 residues), 22.3 bits, see alignment E=3.5e-08 PF04432: FrhB_FdhB_C" amino acids 157 to 322 (166 residues), 87.1 bits, see alignment E=3.3e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0386)

Predicted SEED Role

"putative F420H2-dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8AAS8 at UniProt or InterPro

Protein Sequence (397 amino acids)

>BT0386 putative F420H2-dehydrogenase (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MNKYLNNINASYCCGCSACVHKCPKQCLRMSQDKDGFFFPIVNNREACIDCSLCAKVCPM
ENMVESDYPHTFYGAYNTNKTDIVNSSSGGIYPSLAKWIISQGGIVFGASLDDEHKLYHI
GVSTESDIQKTIGSKYFQSEIRDTYVECKKELDKGRLVLYTGTPCQVHGLKRYLGKDYDN
LYTADVICHGVPSSKMFDAYIDFLEKKHNGKLVDINFRDKKRNGWSITLRYTIEYSNDKR
KDYYLINKLSEYFMAFLGGYIERESCYSCPFSSMRRPGDITMGDFWGYQFKRPDLKHDEG
LSLIIVNSEHGKRIVDVLHRNGVQFNAVDEECVKASENKNLYKPTLRPEVRSVVYDELQN
FGFEYIAKKYFRRTQTLRNKAKNYMPVALVNIIKKLK