Protein Info for BT0138 in Bacteroides thetaiotaomicron VPI-5482

Annotation: transcriptional regulator (NCBI ptt file)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 915 transmembrane" amino acids 733 to 754 (22 residues), see Phobius details PF07494: Reg_prop" amino acids 24 to 47 (24 residues), 19.4 bits, see alignment (E = 1.7e-07) amino acids 420 to 438 (19 residues), 16.1 bits, see alignment (E = 2e-06) amino acids 549 to 571 (23 residues), 18.2 bits, see alignment (E = 4.3e-07) PF07495: Y_Y_Y" amino acids 669 to 721 (53 residues), 47.2 bits, see alignment 3.5e-16 PF12833: HTH_18" amino acids 825 to 906 (82 residues), 55.5 bits, see alignment E=1.2e-18 PF00165: HTH_AraC" amino acids 871 to 906 (36 residues), 31.9 bits, see alignment (E = 2.3e-11)

Best Hits

KEGG orthology group: None (inferred from 100% identity to bth:BT_0138)

Predicted SEED Role

"DNA-binding response regulator, AraC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q8ABH2 at UniProt or InterPro

Protein Sequence (915 amino acids)

>BT0138 transcriptional regulator (NCBI ptt file) (Bacteroides thetaiotaomicron VPI-5482)
MCWVCGENLQAQPYMFRNVVMSDGLSGLLVNAIYKDSEGFIWLGTDNGLDRFDGVKVKHF
EFRGVDSGRKKRVNCITETDNKQLWIGNGIGLWRLNRSGSELQRIVPEKIDCAVNALLAD
GDVLYIGTERGLFIQKDGQLLQVQTDKNMLAACNRIMDLCLNEDKSVLWLATVQGLFSYS
LKDGQINSWHFRENVPEADYFRCLTRIGETLYLGTMSQGVVCFDIPKQTFAHTVSLGCDV
ISDISGDGKETVYIATDGNGVHFLSHKDRKVVRRFFHDVNDKEGIRSNSIYSLLVDDRGA
VWVGHFQAGLDYSLYQNGLFRTYAYPPQFNSANLSIRSFVNRGPEKVIGSRDGLFYINEA
TGIVKSFVKPVLTSDLILTICFYEGEYYIGTYGGGMMVLNPQTLSLKYFTQGDTELFQKG
HIFCVKPDNRGNLWIGTSQGLFCYNGQTKQIKNFTSTNSQLPEGNVYEVSFDSTGKGWIA
TETGMCIYDPASQSLRSNVFPEGFVHKDKVRTIYEDAEHNLYFIREKGSLFTSTLTMDHF
RNQSVLSTLPDNSLMSITEDNQGWLWVGCNDGLLRIKEEGEEYDSFTFNDGVPGPTFTNG
AAYKDERGLLWFGNTKGLIYVDPKQVDEVRGKVRPIVFTDILANGVSINKSSLKYNQNNL
TFCFTDFAYGLPSALLYEYKLEGADSDWKLLTAQSEVSYYGLSSGTYTFCVRIPGNEQSM
AIYKVTVQPMIPWWGWVILAISIILIVVLVRYYVRKSAPLVTEVHEISSEEEEEEEKTAE
PHPAEEKYKANRMSEAECKELHDRLVAYVEKEKPYINPDLKMGELAAALHTSSHSLSYLL
NQYLNQSYYDFINEYRVAQFKKMVEDSDYSRYTLTALAELCGFSSRASFFRSFKKSTGVT
PNEYIRSIGGTAKDE