Protein Info for DVU0510 in Desulfovibrio vulgaris Hildenborough JW710

Name: nusA
Annotation: N utilization substance protein A (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 428 PF08529: NusA_N" amino acids 4 to 128 (125 residues), 115 bits, see alignment E=3.5e-37 TIGR01953: transcription termination factor NusA" amino acids 6 to 344 (339 residues), 398.9 bits, see alignment E=8.2e-124 PF00575: S1" amino acids 136 to 197 (62 residues), 30 bits, see alignment E=8.5e-11 PF13184: KH_5" amino acids 233 to 299 (67 residues), 91.7 bits, see alignment E=3.7e-30

Best Hits

Swiss-Prot: 44% identical to NUSA_BACHD: Transcription termination/antitermination protein NusA (nusA) from Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)

KEGG orthology group: K02600, N utilization substance protein A (inferred from 100% identity to dvu:DVU0510)

Predicted SEED Role

"Transcription termination protein NusA" in subsystem NusA-TFII Cluster or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72EQ9 at UniProt or InterPro

Protein Sequence (428 amino acids)

>DVU0510 N utilization substance protein A (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSMELKKAIDQISKDKGLERDMLVATLEEAVRTSVVRKYGDDIDVEVSYNDESGEIEVYQ
FKIVVAELDDEDEDGNAHIVLEEARKHDPSVQIDDEMGFRLKVEDLGRIAAQSAKQVIIQ
RMRDAEQELIYDEFKDRRGEIISGIIQRRDKAGWIINLGRTEALLPKEEQIPREHYKRGD
RVQAIIIEVRKEGRGPQVIVSRSHRDYMAALFRREVPEVDDGTVQIMGVARDPGSRAKVA
VLSRERDVDPVGACVGIRGSRIQNVVQELRGERIDIVVWSPEIATYARNALSPAVISRIV
VDEEENLLEVIVPDDQLTNAIGRKGQNVKLAAKLLGWKIDIYTETRYNEANAIGRGLEQI
ASVAEISIEQFVTAGFQSIERLREASDEELASGLGIDDNRIADLRAAINFLSPAPSASDG
DDADGETE