Protein Info for DVU0500 in Desulfovibrio vulgaris Hildenborough JW710

Name: selB
Annotation: selenocysteine-specific translation elongation factor (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 642 TIGR00475: selenocysteine-specific translation elongation factor" amino acids 3 to 637 (635 residues), 362.9 bits, see alignment E=3.4e-112 PF00009: GTP_EFTU" amino acids 4 to 165 (162 residues), 115.1 bits, see alignment E=6.2e-37 TIGR00231: small GTP-binding protein domain" amino acids 7 to 161 (155 residues), 44 bits, see alignment E=2.1e-15 PF03144: GTP_EFTU_D2" amino acids 193 to 260 (68 residues), 48 bits, see alignment E=2.9e-16 PF09106: SelB-wing_2" amino acids 455 to 507 (53 residues), 56.5 bits, see alignment 4.9e-19 PF09107: SelB-wing_3" amino acids 590 to 636 (47 residues), 59 bits, see alignment 5.3e-20

Best Hits

Swiss-Prot: 58% identical to SELB_DESBA: Selenocysteine-specific elongation factor (selB) from Desulfomicrobium baculatum

KEGG orthology group: K03833, selenocysteine-specific elongation factor (inferred from 100% identity to dvl:Dvul_2441)

Predicted SEED Role

"Selenocysteine-specific translation elongation factor" in subsystem Selenocysteine metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72ER9 at UniProt or InterPro

Protein Sequence (642 amino acids)

>DVU0500 selenocysteine-specific translation elongation factor (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MPVIMGTAGHIDHGKTSLVRALTGIDCDRLDEEKRRGITIELGFAFCDLPGGGRLGVVDV
PGHEKFVRNMVAGASGVDFVMLVIAADEGVMPQTREHLEICSLLGIRHGLVALTKVDMVD
ADWLELAQDDVAGFLAGTFLEGAPIFPVSAVTGQGLDTLREHLATLERELRPERRTDLFR
LPVDRVFTMRGHGTVVTGTMISGSLKVGDDVVLYPEGRTSKVRGLQSHGGPVDKALAGRR
TAVNLQGVDVAEVQRGEVLALPGTLFPAQRWDVRLTCLSSAARPLRNRTEVHFHHGAREV
LARLHFHDRDRLNPGETALCQVRFTEPMVGVFGDRCVVRTFSPLRTVAGGVVVNPTGHDL
RRRDPHFADKVALLASLPEATEEELVQAHVDLSGNAGAGFVRLSVLTDLESKRLEKVLQA
LGARGRLFCFDREERAYVGADALQALSAGCLDHAGAFHAKEPLKPGMARGVLASGWGRGL
HPRLIHFVVERLIKQGALVAEGDVLRLPGHKVSLASDQEGLRGKLLAIYSEAGMTPPNLK
DVLETLSLEQKEAAPVLKLLHDGGELVRVKDGLLFHRSALDELKGRVARWFDDHDDLDPS
GFKELSGGLSRKYIIPLLEYFDRERVTIRVGDKRQLRGAKAG