Protein Info for DVU0374 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: pyruvate ferredoxin/flavodoxin oxidoreductase family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 832 PF02775: TPP_enzyme_C" amino acids 388 to 522 (135 residues), 41.1 bits, see alignment E=2.4e-14 PF01558: POR" amino acids 645 to 829 (185 residues), 95.8 bits, see alignment E=5.1e-31

Best Hits

KEGG orthology group: K00179, indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC: 1.2.7.8] (inferred from 100% identity to dvu:DVU0374)

Predicted SEED Role

"Indolepyruvate oxidoreductase subunit IorA (EC 1.2.7.8) / Indolepyruvate oxidoreductase subunit IorB (EC 1.2.7.8)" in subsystem Aromatic amino acid interconversions with aryl acids (EC 1.2.7.8)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.8

Use Curated BLAST to search for 1.2.7.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72F41 at UniProt or InterPro

Protein Sequence (832 amino acids)

>DVU0374 pyruvate ferredoxin/flavodoxin oxidoreductase family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MNAIKQLCTQNAGEAAVLQGNIAFAAGCVRSGIHAVDGYPGTPSTEVIDKGLSNVQDMIK
VGWSVSEAVAVSMGHGHSLAGEDCIVTMKIPGLFQAGDPFSSSAFFTEDRGALVYYLASD
FTPSSTQHLVDPRPFIRSCFTPIFEPRNHQEMHEAAEIAADISRQYKTPVVILASGTLCH
SEGLVRLSEIRTRERVVSSVPLKAFNTLPVTARRNYDKVVTERMPALADMVEKSPLNVWE
RGSRKVGVITFGVGEMMVREVKQALGEDIDILSLGFTCPLPMNLIREFHASIEGDVYVVE
DGYRYLQEELERAGLAVKGKSPADTVTEWDPAGIAALLGYSLKSPAASDVAPLPRAPMIC
AGCPYRLFGETVRSMKKRGKIEACFGDIGCNTLLYFMDAMDTNVAMGAGEAHRAGFIVAN
PDKAAKCISLLGDGTECHSGMDATRNTIFRHIAGVKVVLDNNWTAMTGGQPGPTSPVNLA
GQENTFDLQASLKAHGAKVVVVNGYDRKGIRTALTSALEDAANGEFTTMVVTGVCIRKMP
KSAYGTRMTVDADLCKRCGQCQICPGISADAEGLPSFNNLCSGCVSQNAACGQMCPVHAI
KAAEAVDTRATARVELPKAPEEIAMPAPGSFTLPEKIAVAIRGVGGQGNLFFGRVLTQLA
FLAGYGDTNVVKGETHGMAQMGGPVISTFSCGKVVSPVLLPGTADCLVSMEMSEVLRPGY
VGMLRPGGTVLLADTRVLPYGVSEDAYPHRDAILGTLDGYNVIIIDVLKAALELGDPTGR
IANVVMIGALSTLAPFDGFPAELWLQALRNVSPKPAIWTANHAAFNVGRGLL