Protein Info for DVU0271 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: response regulator (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 496 PF00072: Response_reg" amino acids 7 to 114 (108 residues), 103 bits, see alignment E=1.1e-33 PF02518: HATPase_c" amino acids 450 to 494 (45 residues), 27.2 bits, see alignment 4.5e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU0271)

Predicted SEED Role

"Adenylate cyclase (EC 4.6.1.1)" in subsystem cAMP signaling in bacteria (EC 4.6.1.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 4.6.1.1

Use Curated BLAST to search for 4.6.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72FE3 at UniProt or InterPro

Protein Sequence (496 amino acids)

>DVU0271 response regulator (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MNGARLLLVDDEEGIRTVLSLVLADMGHDVRTAANGNEALALLHDRPADVVLTDVRMPGM
DGLALLAAVREAWPDTGVIMLTGHGDMELAVKSLRLGATDFLTKPVGDEALSVALDRAFE
RRRLRMALRAHTEHLEALVEARTRELVEAERLAGMGETAAMLAHAIKNIASSLEGGLFVL
GKGIELGRRDYLEDGWGLVREHVARVRDLALHLLNLGKPLTGDAAPVDPDAPVREVVQLL
TARARERGVALSMAYGAGPTPLVLDGEAVRRVLTDLILNAIEAFSLPEGRSGEAAVHVSS
FRAEWLDGRAAVRYVVRDNGPGLPMRLRPERREEAVAALLAGCLAGHGDLSPSVVPSQGE
DCAPVDAAGTGKGTGTGMGALSAEASTGTHPVADVAMGGGDAALQLSPVSDDGIVLGGGG
GASVFPSPGDDPARWGVDAVTGEALRGRLQTTKQGGSGVGLLTVRRIVHELGGEFRLGDA
EGGGCEATVALPVAHS