Protein Info for DVU0246 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: pyruvate phosphate dikinase, PEP/pyruvate binding domain protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 744 PF01326: PPDK_N" amino acids 13 to 326 (314 residues), 177.7 bits, see alignment E=3.9e-56 PF00391: PEP-utilizers" amino acids 373 to 445 (73 residues), 47.9 bits, see alignment E=9e-17

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU0246)

Predicted SEED Role

"PEP/pyruvate binding domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72FG7 at UniProt or InterPro

Protein Sequence (744 amino acids)

>DVU0246 pyruvate phosphate dikinase, PEP/pyruvate binding domain protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MLPLSEVAGRPEVAGHKASRLAEVRQRTMLPVPDGFVVTASAFHYIIEYNGLRAPLDDLL
RQVDLADGNSLVDLCRTMRELVLTVELPPVLETELLEAGHALSPQRAPLAVRSSAVAEDG
EASFAGQHTSVLGVAPADLPDAYRTVLAGKYTPRAVSYRIIHGFADTETPMAVLLMPLVQ
AKASGVAYTRAPSPPARILSLAATGRAAKTSEDDNGTPSTTATATKAPDAPAASDDSAAG
VIAIHTVGGMGAPLMDGSSGDTTAWLSRGARHRILERAQGLPLTTEDLKRLARLSMELET
LFGEPQDVEWAIDESGRISIVQSRPVPGAAVAPPPRVDVSGLTPLLEGADPVAPGTGCGT
VVHVLSCADIGDLPPGTVLVTPCLGPSLARVLDRMEGVISVEGSRASHFASVARESSVPV
LVTGDDSVFATLPVGTLVTVDAHEGVVFAGRPATPPPRRSSPGAMALRGPMHRLSRAMPH
VARLTLVDPSSSDFAPANCRSLHDIVRFCHEMAVREMFSLVERDGRGLSGARKVRGDIPV
VMYVLNLDDGFFPSAIGKREITPDDFRSLPLWAIWFGLSSEPAAWAALPPAADWEELDRI
SAGIFRRDSPQLASYAVASSTYANIMLRFGYHFAVIDSLCAGDTRANYIQFRLKGGGGHA
EGRSLRLRFLSRVLEQSGFSTRIKGDLIDARHGPGSEALIQKRLALLGRVLAVTRLMDIR
LSTEEQADAEADNFLTRINTPEDD