Protein Info for DVU0062 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: RND efflux system, outer membrane protein, NodT family (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 10 to 465 (456 residues), 404.7 bits, see alignment E=2.6e-125 PF02321: OEP" amino acids 59 to 250 (192 residues), 97 bits, see alignment E=6.1e-32 amino acids 285 to 463 (179 residues), 108.4 bits, see alignment E=2e-35

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvl:Dvul_2899)

Predicted SEED Role

"Outer membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72G01 at UniProt or InterPro

Protein Sequence (504 amino acids)

>DVU0062 RND efflux system, outer membrane protein, NodT family (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MIRRMTAMLLGAALLSGCAIGPDYQRPGMDLPSAWRAESADAGMVAGEKWWTLFGDATLD
ALEEEALAANGDLATAMANVDASRAQLTVATSYLLPSITGQGSSVRQRGSERGQNPPVEG
REVTDLHKASALASFELDLWGKYRRAHEAARAGLLGTEAAYATVRLAVVSQVAQSYFGLR
AADRQLDIARQTLTSREESLKIREARFNSGLTSELDYRQAQAETASARASVRQLEQAVAA
AETALSSLLGRSPRDIVERSPERGLDIETFAVPPQIPAGLPAGLLARRPDVARAEADLHY
ATASIGVAKADLLPAISLTGLMGYESIDLTRLVSSSSGTWSYGASATMPLLDFGRTLANI
DMADAKQRAALAAYEQAVRDAFRETQDALVANRKTRQVVDAQATQVAALERSLTLARLRY
ENGYSSYLEVLDAERSLFQAQLNLVEARRNQLDAVVQVCKSLGGGWKAPGEEGADATGAA
EAASGDADDAAPQGVAPTPPRTEG