Protein Info for DVU3187 in Desulfovibrio vulgaris Hildenborough JW710

Name: hup-4
Annotation: DNA-binding protein HU (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 75 95 PF00216: Bac_DNA_binding" amino acids 2 to 94 (93 residues), 90.4 bits, see alignment E=3.5e-30

Best Hits

Swiss-Prot: 37% identical to IHFB_RHORT: Integration host factor subunit beta (ihfB) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)

KEGG orthology group: K03530, DNA-binding protein HU-beta (inferred from 100% identity to dvl:Dvul_0200)

Predicted SEED Role

"DNA-binding protein HU" in subsystem DNA structural proteins, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q725K7 at UniProt or InterPro

Protein Sequence (95 amino acids)

>DVU3187 DNA-binding protein HU (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MLTKAEFVAALKDSLPDVFETKVSAEKAYDTFCKIMADGVANGQGVRLPGVGALTVTERA
ARTGRNPQTGQTITIPARKAVKFAAAKALLDGING