Protein Info for DVU3162 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: ABC transporter, periplasmic substrate-binding protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 431 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF01547: SBP_bac_1" amino acids 48 to 337 (290 residues), 116.2 bits, see alignment E=3.2e-37 PF13416: SBP_bac_8" amino acids 51 to 366 (316 residues), 141.5 bits, see alignment E=4.8e-45

Best Hits

KEGG orthology group: K05813, sn-glycerol 3-phosphate transport system substrate-binding protein (inferred from 100% identity to dvl:Dvul_0224)

Predicted SEED Role

"Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein (TC 3.A.1.1.3)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization (TC 3.A.1.1.3)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q725I7 at UniProt or InterPro

Protein Sequence (431 amino acids)

>DVU3162 ABC transporter, periplasmic substrate-binding protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MALFRKTCALVAASLLSLTLMAGTALAEKVNLTFYFPVSVGGPITKIVEGMTEQFMKEHP
DINITPVYAGIYRETLTKALTALRGGEPPHVAVLLSTDMYTLIDEDAIVPYDSIMKPEEM
AFTKAFFPGFMSNSQTGGKTWGIPFQRSTIVMYWNKEAFKAAGLDPDKAPANWQELVAMG
KKLTVKDESGKVTQWGVAIPSTGYAYWMLQALAIQNGVELMNAEGTKTYFDDPKAIEALT
FLVDLAGKHGVSPSGTIDWATTPRDFFERKTAIMWTTTGNLTNVRKNAQFPFGVGMLPAN
TRPGSPTGGGNFYIFKKSTPAERQAAVTFVKWMTSAERAAQWGIDTGYVAVRPDAWETKA
MKDYVASFPYAAIARDQLAHGVAELSTHDNQRVTKALDDAIQAAVTGSKTPAEALKAAQK
EAERILRRYAK