Protein Info for DVU3091 in Desulfovibrio vulgaris Hildenborough JW710
Annotation: conserved hypothetical protein (TIGR)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00278, L-aspartate oxidase [EC: 1.4.3.16] (inferred from 100% identity to dvu:DVU3091)Predicted SEED Role
"L-aspartate oxidase (EC 1.4.3.16)" in subsystem NAD and NADP cofactor biosynthesis global or NAD regulation (EC 1.4.3.16)
MetaCyc Pathways
- aspartate superpathway (20/25 steps found)
- NAD de novo biosynthesis I (6/6 steps found)
- nicotine biosynthesis (3/9 steps found)
- superpathway of nicotine biosynthesis (4/12 steps found)
KEGG Metabolic Maps
- Alanine and aspartate metabolism
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Nicotinate and nicotinamide metabolism
Isozymes
Compare fitness of predicted isozymes for: 1.4.3.16
Use Curated BLAST to search for 1.4.3.16
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q726L5 at UniProt or InterPro
Protein Sequence (448 amino acids)
>DVU3091 conserved hypothetical protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710) MSFETDIIVAGTGLAAYAAAIAAAERTPRLSVTLVGRPGPIPPSGSLRLLAPSEDAAREW CLAALTELSQPGAFEPALASLMVDESHVAADFLAASGVALPPRSRLRLGGDYIPLCRSIL DAGPMAEVKARLRARALAAGVDIHEGLRLVTIGADDGPPGSAICTDMHDETVRLRARAVV LAERGCAPLFVPDAQQDVAAGLGLGLLRQTRAVLGNAAFIQMVWRTVDDEPFDLGLAAGS PSFEVAGPGGVFTRLPRPLVALASERATHKAHAWSRADNAIDVHLLDCMTPAGVVNIRHE RQPLRIVPAVVSATGGARISVDGATNLTGLYACGGCATGMFGADVLEGSHATAALVFGIR AGIGATRHACSALMPPPPEHRPPMPPRRLPLRLREALLQHCLPGHRPGLQALIERLRALA SLPSLTPLEHCRVLSALTVAEFRSALLH