Protein Info for DVU3025 in Desulfovibrio vulgaris Hildenborough JW710

Name: por
Annotation: pyruvate-ferredoxin oxidoreductase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1215 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR02176: pyruvate:ferredoxin (flavodoxin) oxidoreductase" amino acids 5 to 1169 (1165 residues), 1989.3 bits, see alignment E=0 PF01855: POR_N" amino acids 17 to 248 (232 residues), 274.3 bits, see alignment E=6.3e-85 PF17147: PFOR_II" amino acids 269 to 372 (104 residues), 51.6 bits, see alignment E=6.8e-17 PF01558: POR" amino acids 425 to 609 (185 residues), 127.7 bits, see alignment E=3.6e-40 PF10371: EKR" amino acids 631 to 677 (47 residues), 66.3 bits, see alignment (E = 1.1e-21) PF00037: Fer4" amino acids 683 to 704 (22 residues), 22.6 bits, see alignment (E = 4.7e-08) PF13183: Fer4_8" amino acids 686 to 757 (72 residues), 31.1 bits, see alignment 1.8e-10 PF13237: Fer4_10" amino acids 686 to 755 (70 residues), 30.1 bits, see alignment 2.5e-10 PF13484: Fer4_16" amino acids 687 to 756 (70 residues), 34.4 bits, see alignment 2e-11 PF12838: Fer4_7" amino acids 687 to 757 (71 residues), 35.2 bits, see alignment 9.1e-12 PF02775: TPP_enzyme_C" amino acids 955 to 1067 (113 residues), 37.1 bits, see alignment E=1.8e-12

Best Hits

Swiss-Prot: 71% identical to PFOR_DESAF: Pyruvate:ferredoxin oxidoreductase (por) from Desulfovibrio africanus

KEGG orthology group: K03737, putative pyruvate-flavodoxin oxidoreductase [EC: 1.2.7.-] (inferred from 61% identity to amt:Amet_1676)

Predicted SEED Role

"Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)" in subsystem Methionine Degradation or Pyruvate:ferredoxin oxidoreductase (EC 1.2.7.-)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.-

Use Curated BLAST to search for 1.2.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q726T1 at UniProt or InterPro

Protein Sequence (1215 amino acids)

>DVU3025 pyruvate-ferredoxin oxidoreductase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MAKKMKTMDGNTATAYVAYALSDTAAIYPITPSSNMGEAADEWAAQGKKNIFGQTVAVRQ
LQSEAGAAGAVHGCLAAGALTSTYTASQGLLLMIPNMYKISGELLPGVFHVSARAIAAHA
LSIFGDHQDVMAARQTGFAMLASTSVQECMDLALVSHLSAIESSVPFCHFFDGFRTSHEL
QKIEVIDYDDMKKLVNWEKVENFRQNAMNPEHPHIRGTAQNPDIYYQAREAANPFYAAVP
GIVASYMKKVGEITGRKYKPFDYVGHPEADRVIIAMGSGCETIEEVVNYLNAAGQRVGLV
KVRLYRPFSVEHLMAVLPASADTITVLDRTKEPGALGEPLYLDVCTAFMERGEMPKLIAG
RYGLGSKEFTPAMVKAVYDNMKVNGPKNHFNVGIIDDVTDTSLEVEADLDTVPTGTVQCK
FFGLGADGTVGANKQAIKIIGDNTDMYAQGYFAYDSKKSGGFTVSHLRFGKSPIQSTYLV
NRADYVACHKSAYVNQYDVLEGIKEGGTFVLNSHWTSVEDMERELPASMRRTIARKQLKF
YNVDAVKVATEVGLGGRINMIMQTAFFKLASVIPFEQAVELLKDSIKKAYGKKGDKIVNM
NIAAVDKAIDALQEVKYPASWADAVDVPVACAEEPGFITDVVRPILAQQGDKLPVSSFEP
DGLFPVGTAAFEKRGVAINVPEWLSENCIQCNQCSFVCPHAAIRPVLATTEELEGAPASF
VTIDAKGKELNGLKYRIQVFAQDCLGCGSCAEVCPAKNKALVMKPIETQLDAQVPNLAFA
EENIAIKDDLMGRDSLKGSQFQQPLMEFSGACAGCGETPYVKLLTQMFGERMIVANATGC
SSIWGASAPTTPYCTNKDGHGPAWGNSLFEDAAEFGYGMGMAFNQRRAKLADLVKEALEL
DIPAELRAAFEGWLAGKDDAEASRKYGDEILALLGTADDHPVLHEMWHMSDLFTKKSVWI
FGGDGWAYDIGYGGVDHVLASGEDINILVMDTEVYSNTGGQSSKATPLGSIAKFAASGKK
TGKKDLGRMAMTYGYVYVASISMGANKQQVLKAFKEAEAYKGPSLIIAYAPCINQGIRKG
MGKSMEEGKLAVESGYWPLYRFNPELADQGKNPFVLESKAPDGTMQDFLAGENRYALLEK
IAPEESKRLRAQIEKEYVERYSMLKQMAEAPAVTAAPGAPVAAAGEAGENCTVSETPEHA
RTNGGSACDDGRSGK