Protein Info for DVU2931 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: sensory box histidine kinase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 733 transmembrane" amino acids 26 to 46 (21 residues), see Phobius details amino acids 53 to 73 (21 residues), see Phobius details amino acids 94 to 114 (21 residues), see Phobius details amino acids 294 to 316 (23 residues), see Phobius details PF19312: NtrY_N" amino acids 31 to 306 (276 residues), 44.2 bits, see alignment E=7.2e-15 PF00672: HAMP" amino acids 318 to 367 (50 residues), 58.6 bits, see alignment 2.8e-19 PF00989: PAS" amino acids 395 to 504 (110 residues), 41.3 bits, see alignment E=6.5e-14 TIGR00229: PAS domain S-box protein" amino acids 395 to 512 (118 residues), 44.8 bits, see alignment E=6.5e-16 PF08448: PAS_4" amino acids 399 to 509 (111 residues), 44.8 bits, see alignment E=6.1e-15 PF13426: PAS_9" amino acids 405 to 506 (102 residues), 30.3 bits, see alignment E=1.9e-10 PF00512: HisKA" amino acids 516 to 581 (66 residues), 40.8 bits, see alignment E=8.4e-14 PF02518: HATPase_c" amino acids 625 to 732 (108 residues), 92.4 bits, see alignment E=1.1e-29 PF14501: HATPase_c_5" amino acids 629 to 715 (87 residues), 28.6 bits, see alignment E=5.1e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU2931)

Predicted SEED Role

"Nitrogen regulation protein NtrY (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q727C4 at UniProt or InterPro

Protein Sequence (733 amino acids)

>DVU2931 sensory box histidine kinase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MPTGTEDAQRRHEELTRERRRRQRELIAAGVLVLVVLVATWVELTFFGVDSWMFLALFNV
NLLLSLVVLFLVVRNSIKLLVERRRNVPGAKLRTRLVLMFMLLSLAPTVIMFLASNRVVA
TSVDYWFKNQAENAMDAALDVGQSFYTASASRLRARAELISREVAERRTPWGSPAADALL
DRRAREYGLIAVGFVTPAHAERNWHAPSEFAPVWDEARKRIAWDHVAAQRFGSLLWAGDT
ADYVIGALAIDAGRTGYLVVAESIGQGLMLKLDRISKGFEEYKSLKNLKRPLKVSFTLIL
GILSLLVVLGALWLGLRLSRELTAPILALADGADRIAKGDLDVRLEDSAQDEIGQLVRAF
NKMAGDLAHNRQSLTEANRLLAQSNAEIAGRNAYIEAVLDNIAAGVISLDASGRIQTVNK
AAASILGTPSERLKGRRPAAFLDGPYLDIIDDMLTQLHRRPEMHWERQMDLSGSDRALKL
LVHAVALRGVDGSVDGIVAVFEDISELERMQRMAAWREVARRIAHEIKNPLTPIKLSAQR
LERKFGPRVDDPVFGQCTALIVKQVEHLQQMVQEFSTFAKLPEVTPRAGDITPLLEEVTG
LFRHGHSRIAWQVDIAPALPPVRMDGEALHRAFINILTNAIEALEGTATPSINVQASHDA
ERARVRVEIADNGPGLTPEERSRMFEPYFTSKKGGTGLGLSIVRSIVNDHGGHVRAAGAP
GGGTVVTVELPVA