Protein Info for DVU2682 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: DedA family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 213 transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 55 to 79 (25 residues), see Phobius details amino acids 126 to 146 (21 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 187 to 205 (19 residues), see Phobius details PF09335: VTT_dom" amino acids 49 to 173 (125 residues), 66.9 bits, see alignment E=1.2e-22

Best Hits

Swiss-Prot: 51% identical to DEDA_ECOLI: Protein DedA (dedA) from Escherichia coli (strain K12)

KEGG orthology group: K03975, membrane-associated protein (inferred from 100% identity to dvu:DVU2682)

Predicted SEED Role

"DedA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q728C2 at UniProt or InterPro

Protein Sequence (213 amino acids)

>DVU2682 DedA family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MEMLTHLIDLLLHVDKYLFQLVGEYGTLTYAILFCIVFCETGLVVTPFLPGDSLLFAAGT
IAGAGHLDYPTLMGVLLAAAVGGDAVNYEIGRHVGPAIFERETRFLNKQHLQRAHDFYER
HGGKAIVLARFIPIVRTFAPFVAGVATMCPTRFFMFNISGGILWVTSLVSAGYFLGNTPF
VQRNFSVLIYAIIVVSVLPIAVDLVRSRMRRRG