Protein Info for DVU2555 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: MATE efflux family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 473 transmembrane" amino acids 24 to 43 (20 residues), see Phobius details amino acids 60 to 84 (25 residues), see Phobius details amino acids 96 to 117 (22 residues), see Phobius details amino acids 135 to 156 (22 residues), see Phobius details amino acids 164 to 189 (26 residues), see Phobius details amino acids 196 to 218 (23 residues), see Phobius details amino acids 241 to 267 (27 residues), see Phobius details amino acids 292 to 313 (22 residues), see Phobius details amino acids 325 to 346 (22 residues), see Phobius details amino acids 366 to 388 (23 residues), see Phobius details amino acids 397 to 419 (23 residues), see Phobius details amino acids 426 to 446 (21 residues), see Phobius details PF01554: MatE" amino acids 23 to 179 (157 residues), 72.7 bits, see alignment E=1.4e-24 amino acids 248 to 413 (166 residues), 74.4 bits, see alignment E=4.5e-25 TIGR00797: MATE efflux family protein" amino acids 23 to 426 (404 residues), 155.3 bits, see alignment E=1.1e-49

Best Hits

KEGG orthology group: K03327, multidrug resistance protein, MATE family (inferred from 100% identity to dvl:Dvul_0693)

Predicted SEED Role

"Multidrug and toxin extrusion (MATE) family efflux pump YdhE/NorM, homolog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q728P8 at UniProt or InterPro

Protein Sequence (473 amino acids)

>DVU2555 MATE efflux family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTVTSSIAAGDASFRGIWRLTWPQMLMMLFQFIIGFTDVWVAGRINPDVQASLGIVNQCM
FFLLVVAVALSNGAVAAVGQALGAGLLARARRYVSLILWGGALCGGVVAASGLVAADALL
HVLMVPERIMPVASYFWHVYLLTLPAHYLFTISNAAFRARKDVIAPLLTMVVVSVVNAVA
SAGFGLGLWGLPDFGYAGVAWGTFWSVLAGAALNVVLLRRGGMVQGVSMPPWRWIRCGAP
YLVKVAAPAAAMQVLWHMGYLVLFAITGSLPAPADSVNALAGLTAGMRVESLIFLPAFAF
NMTASILVGHLLGAGLRDDARRVGLRLLVIGCGSMTVLAALLWPWVPELSAILTPDAAVA
AQTVSYLRYNLVSIPFTVASMTLGGIMTGAGATFYNFIVYSSATWFVRLPCAWFMGHVVW
RDAAGVFIAMLVSQVFQSSTMFWLFLTKDWSRFSMMRRANGTTHKGGNSNVRD