Protein Info for DVU2507 in Desulfovibrio vulgaris Hildenborough JW710

Name: mraY
Annotation: phospho-N-acetylmuramoyl-pentapeptide-transferase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 transmembrane" amino acids 27 to 48 (22 residues), see Phobius details amino acids 69 to 90 (22 residues), see Phobius details amino acids 96 to 113 (18 residues), see Phobius details amino acids 133 to 152 (20 residues), see Phobius details amino acids 170 to 190 (21 residues), see Phobius details amino acids 197 to 216 (20 residues), see Phobius details amino acids 233 to 253 (21 residues), see Phobius details amino acids 260 to 280 (21 residues), see Phobius details amino acids 286 to 308 (23 residues), see Phobius details amino acids 336 to 355 (20 residues), see Phobius details TIGR00445: phospho-N-acetylmuramoyl-pentapeptide-transferase" amino acids 37 to 358 (322 residues), 408.2 bits, see alignment E=1.4e-126 PF10555: MraY_sig1" amino acids 67 to 78 (12 residues), 23.2 bits, see alignment (E = 3.5e-09) PF00953: Glycos_transf_4" amino acids 98 to 281 (184 residues), 121.8 bits, see alignment E=2.8e-39

Best Hits

Swiss-Prot: 100% identical to MRAY_DESVH: Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K01000, phospho-N-acetylmuramoyl-pentapeptide-transferase [EC: 2.7.8.13] (inferred from 100% identity to dvl:Dvul_0738)

Predicted SEED Role

"Phospho-N-acetylmuramoyl-pentapeptide-transferase (EC 2.7.8.13)" in subsystem Peptidoglycan Biosynthesis (EC 2.7.8.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q728U5 at UniProt or InterPro

Protein Sequence (358 amino acids)

>DVU2507 phospho-N-acetylmuramoyl-pentapeptide-transferase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MLYNLLYPLSSDITVFNVFRYITFRSAWALATALLVSIVVGPRFIAWLQRLKCRQFIHED
VTCHMSKAGTPTMGGLLIGFAVTFSVLLWADLRNPYIWLTLLVFTGFGFIGFLDDYTKLR
RRNNKGLTASAKFLWQVGVAVAAMYLLVQLPAYSTKLAFPFFKGLTPDLGWLYIPFAVAV
MVGSSNGVNLTDGLDGLAIGPTIVAGIVFSIFIYVAGHSQIAGYLQVPYVPGVGEVAVFC
GALVGAGLGFLWFNAYPAQVFMGDVGSLSLGGTLGFLAVLCKQELLLLVVGGLFVVETLS
VILQVGYFKFSGGKRIFRMAPLHHHFELQGIPESKIIIRFWITSALLGLIALSVLKLR