Protein Info for DVU2505 in Desulfovibrio vulgaris Hildenborough JW710

Name: ftsW
Annotation: cell cycle protein, FtsW/RodA/SpoVE family (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 377 transmembrane" amino acids 23 to 46 (24 residues), see Phobius details amino acids 63 to 81 (19 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 160 to 190 (31 residues), see Phobius details amino acids 197 to 217 (21 residues), see Phobius details amino acids 280 to 302 (23 residues), see Phobius details amino acids 318 to 340 (23 residues), see Phobius details amino acids 351 to 372 (22 residues), see Phobius details TIGR02614: cell division protein FtsW" amino acids 22 to 375 (354 residues), 412.3 bits, see alignment E=8.5e-128 PF01098: FTSW_RODA_SPOVE" amino acids 25 to 376 (352 residues), 340.6 bits, see alignment E=5.2e-106

Best Hits

Swiss-Prot: 42% identical to FTSW_GEOS8: Probable peptidoglycan glycosyltransferase FtsW (ftsW) from Geobacter sp. (strain M18)

KEGG orthology group: K03588, cell division protein FtsW (inferred from 100% identity to dvu:DVU2505)

Predicted SEED Role

"Cell division protein FtsW" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q728U7 at UniProt or InterPro

Protein Sequence (377 amino acids)

>DVU2505 cell cycle protein, FtsW/RodA/SpoVE family (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTRKSPLGQVLSRAEGPTGPVDWWLFGIVLLLLGIGLMMVLSASGIVAERFNHDKYLFFK
KQLVFAAGGGITMWVAALMPRHMLYKLQYPALFGVIALLLLTLTPVGAKINGARRWIPLG
PVALQPMEFSKIALAMYLAYFMSTKQEIIKTFSRGVIPPYAVTGLLCLLLLLQPDFGGAA
VLAMILFFMCLVGGTRFIYLFVSLAFAIMGAWALIVHSPYRFRRLLAFIDPFKDAQDTGY
QLVQSLYAFGSGGFTGVGIGASRQKLFYLPEAHNDFIMAVLGEELGLIGVTIVMTLFALL
FWRSFKIILGQHDLRDRFTAFGVTMVLLLGAVLNLAVVMGVAPPKGVPMPFLSYGGSSML
SSLICVGLLLNFSRTAR