Protein Info for DVU2451 in Desulfovibrio vulgaris Hildenborough JW710

Annotation: L-lactate permease family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 570 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 33 to 53 (21 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 104 to 123 (20 residues), see Phobius details amino acids 129 to 151 (23 residues), see Phobius details amino acids 156 to 175 (20 residues), see Phobius details amino acids 205 to 226 (22 residues), see Phobius details amino acids 238 to 259 (22 residues), see Phobius details amino acids 265 to 282 (18 residues), see Phobius details amino acids 325 to 342 (18 residues), see Phobius details amino acids 372 to 393 (22 residues), see Phobius details amino acids 414 to 434 (21 residues), see Phobius details amino acids 453 to 475 (23 residues), see Phobius details amino acids 484 to 487 (4 residues), see Phobius details amino acids 489 to 489 (1 residues), see Phobius details amino acids 505 to 532 (28 residues), see Phobius details amino acids 544 to 566 (23 residues), see Phobius details TIGR00795: transporter, lactate permease (LctP) family" amino acids 5 to 561 (557 residues), 359.3 bits, see alignment E=2e-111 PF02652: Lactate_perm" amino acids 7 to 560 (554 residues), 374.8 bits, see alignment E=4e-116

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU2451)

Predicted SEED Role

"L-lactate permease" in subsystem Lactate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q729A1 at UniProt or InterPro

Protein Sequence (570 amino acids)

>DVU2451 L-lactate permease family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSIELLALVALLPILVALVLMVGLRFPATRAMPLAWLVCVIGAIGVWNLPAGYVSALTLQ
GIVTAIGVLIIVFGAIIILYTLQYSGGMETIQYGMQNVSRDKRIQAIIVGYMFAAFIEGA
AGFGTPAALAAPLLLSLGFPPLAAAVICLVFNSFPVSFGAVGTPVLIGLKFLAPLTQEAV
AQGIPGLNFTDFGSFAKVIGQWATLMHGPMIVILPIFMLGFLTRYFGEKKSWVEGFKAWK
FCVFSAVAFAVPYYVFAWFVGPEFPSLIGGLVGLGIIVAGAKRGFCVPETPWDFGPQSSW
DAEWTGSIRTAANTEFKAHMSQFRAWLPYVLIGLILVVTRIPELGLKGFLSAQKIPFNDI
LGYKGVSASIDYLYLPGTIPFTLVALLTILLHGMKGDAVKRAWGESIAKMKSPTIALFFA
VALVSIFRGSGVVDAALNPNAYPSMPLAMAKAVAAVAGNAWPMLASFVGGLGSFITGSNT
VSDLLFAEFQWGVAAQLSMPRQVIVAAQVVGGAMGNMVCIHNIVAVCAVVGLTGREGTLL
KRCFLPFVLYGVVVGVVASLMSFVFLPHLF