Protein Info for DVU2350 in Desulfovibrio vulgaris Hildenborough JW710

Name: gid
Annotation: gid protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 474 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF00070: Pyr_redox" amino acids 11 to 44 (34 residues), 26.3 bits, see alignment (E = 2.5e-09) TIGR00137: tRNA:m(5)U-54 methyltransferase" amino acids 11 to 442 (432 residues), 533.8 bits, see alignment E=1.6e-164 PF07992: Pyr_redox_2" amino acids 12 to 147 (136 residues), 26.9 bits, see alignment E=9.5e-10 PF00890: FAD_binding_2" amino acids 12 to 42 (31 residues), 23.6 bits, see alignment (E = 8.7e-09) PF01134: GIDA" amino acids 12 to 380 (369 residues), 319.5 bits, see alignment E=1e-98 PF13450: NAD_binding_8" amino acids 13 to 49 (37 residues), 27.7 bits, see alignment 8e-10

Best Hits

Swiss-Prot: 100% identical to TRMFO_DESVH: Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO (trmFO) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K04094, glucose inhibited division protein Gid (inferred from 100% identity to dvu:DVU2350)

Predicted SEED Role

"tRNA:m(5)U-54 MTase gid" in subsystem Conserved gene cluster associated with Met-tRNA formyltransferase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q729K0 at UniProt or InterPro

Protein Sequence (474 amino acids)

>DVU2350 gid protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MEDSLTTITTAAIIGAGLAGCECALRLARAGVRVTLFEMKPAAFSPAHSNPDLGELVCSN
SLRSDDIASGVGLLKQEMRELGSIVMEAADATRVPAGKALAVDRDLFARHITAVIEAEPG
ITLERREVASLDDPALASADVVVIAAGPLASAGLSDSLAAVVGGQLYFYDAIAPIIAAES
IDLSIVFSGSRYGEPGEEGDYLNCPMNRDEYDAFYEALLAAEKVPSRDFEKELHFEGCMP
IEALAERGPRTLVFGPFKPVGFTDPRTGTRPYAIIQLRAENRNKTAFNIVGCQTKLKYAE
QERVFRMIPGLAGAEFVRHGSVHRNTYVNAPRVLADDLSLRADKRVFLAGQITGVEGYVE
SAACGMWLGMVLAARIQGRELPTPPPQTALGALLMHLRTPVKNFQPSNANFGLMPELGLK
VKKRERKPLYSARAREHFVRWLAEAGVTPVIEPLLPTAPDTTGAAGEETTQAES