Protein Info for DVU2137 in Desulfovibrio vulgaris Hildenborough JW710
Name: sucCD
Annotation: succinyl-CoA synthetase, alpha/beta subunit (sucCD) (Chris Hemme)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01902, succinyl-CoA synthetase alpha subunit [EC: 6.2.1.5] (inferred from 100% identity to dvu:DVU2137)Predicted SEED Role
No annotation
MetaCyc Pathways
- reductive TCA cycle I (9/11 steps found)
- incomplete reductive TCA cycle (6/7 steps found)
- TCA cycle V (2-oxoglutarate synthase) (7/9 steps found)
- pyruvate fermentation to acetate VI (2/3 steps found)
- superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass (18/26 steps found)
- pyruvate fermentation to acetate V (1/3 steps found)
- TCA cycle I (prokaryotic) (6/10 steps found)
- TCA cycle III (animals) (6/10 steps found)
- TCA cycle VIII (Chlamydia) (3/6 steps found)
- TCA cycle II (plants and fungi) (5/9 steps found)
- reductive TCA cycle II (7/12 steps found)
- superpathway of glyoxylate bypass and TCA (7/12 steps found)
- superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle (14/22 steps found)
- adipate biosynthesis (1/5 steps found)
- adipate degradation (1/5 steps found)
- anaerobic energy metabolism (invertebrates, mitochondrial) (2/10 steps found)
- superpathway of anaerobic energy metabolism (invertebrates) (6/17 steps found)
- methylaspartate cycle (6/19 steps found)
- Methanobacterium thermoautotrophicum biosynthetic metabolism (22/56 steps found)
KEGG Metabolic Maps
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- C5-Branched dibasic acid metabolism
- Citrate cycle (TCA cycle)
- Propanoate metabolism
- Reductive carboxylate cycle (CO2 fixation)
Isozymes
No predicted isozymesUse Curated BLAST to search for 6.2.1.5
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q72A60 at UniProt or InterPro
Protein Sequence (709 amino acids)
>DVU2137 succinyl-CoA synthetase, alpha/beta subunit (sucCD) (Chris Hemme) (Desulfovibrio vulgaris Hildenborough JW710) MFVRSVIAFATPNPTGLTMFLNEHQSKRLFEEAGIETPQGIMTDSAGIEGCLPPFDAPWF VKAQVLAGGRGKAGGVRRADDLAGLRDVAKDILGMRIGGHAVPFVRIEPATAIARECYVS FMVSRKRRELLFTASGSGGVEVESGQGALVCAVPLTGEMPEHVIRSAFFCIGVGREHWAG FREFVLRLHGAVRDYGLLLAEVNPLVLTGDGRWLALDGKVEVDDNVVDIRPDLLRFHTPE HLAPEENAAREAGLSYVELKGWVGLLVNGAGLAMATMDLLNFSGLAAANFMDLGGAADVP RMRRALELLFGNPQVRVVCVNLFGGIVSCAAVAGALVEALGDGRAAKPVVVRMDGFEAAE GRQLLERRAHPDVHVARDIDHALDLLRHLRPADAPDIVFTPGTEKPVPRIHGGAAGTRRG TPHLGKGARVLVQGITGRSAQLHTRLMLDYGTNIVAGVTPFKGGQVTQGVPVYDSVHEAC RQHDIDATILFVPAAFAADSLLEAVAEGIPWAVCITEGIPQKDMLRALRVARGARTRIIG PNTPGIIVPGACKVGIMPGNVFSPGPLAVFSRSGTLTYEAAARLSAAGIGQSLCAGVGGD PYIGSDFVSLCELVRDDEATQGVLVLGEVGGTAEEELAAWVRETAFPKPVVSFVAGRTAP PGRRLGHAGAILDEADGGIAGKVRALCDAGIAVCPDLGSLPAAVRQALG