Protein Info for DVU2110 in Desulfovibrio vulgaris Hildenborough JW710

Name: b2975
Annotation: L-lactate permease (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 545 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 40 to 60 (21 residues), see Phobius details amino acids 69 to 92 (24 residues), see Phobius details amino acids 115 to 134 (20 residues), see Phobius details amino acids 138 to 161 (24 residues), see Phobius details amino acids 167 to 185 (19 residues), see Phobius details amino acids 197 to 216 (20 residues), see Phobius details amino acids 223 to 241 (19 residues), see Phobius details amino acids 249 to 268 (20 residues), see Phobius details amino acids 299 to 318 (20 residues), see Phobius details amino acids 320 to 321 (2 residues), see Phobius details amino acids 356 to 378 (23 residues), see Phobius details amino acids 396 to 416 (21 residues), see Phobius details amino acids 425 to 449 (25 residues), see Phobius details amino acids 521 to 542 (22 residues), see Phobius details TIGR00795: transporter, lactate permease (LctP) family" amino acids 5 to 536 (532 residues), 558.8 bits, see alignment E=7.2e-172 PF02652: Lactate_perm" amino acids 15 to 534 (520 residues), 560.6 bits, see alignment E=1.9e-172

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvu:DVU2110)

Predicted SEED Role

"L-lactate permease" in subsystem Lactate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72A87 at UniProt or InterPro

Protein Sequence (545 amino acids)

>DVU2110 L-lactate permease (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MLWTQVYDPFSNITLSAMVAMLPLAILFYMLAVRRAKGHVAAACGLAGAFAATVAVWGMP
AGLAVNATLYGVAMGLFPIIWIVLTAVWLYNMTVESGEFEIIKSSLARLTDDRRLQALFI
AFAFGAFLEGTAGFGTPVAITAAMLMGLGFSPVYAGGICLIANTAPVAFGALGIPVIVAS
QVSGLDTLTLSQYVGRQLPVFSLIVPLWMTVVMCGFKRTMEVMPAIVVASVCFSGTQFIF
ADWHGPTLPDVMAAIVTIVGLLVLLRFWKPARTWHFADEKPEAATGETRHSTGEVLRAWA
PYAILAVFVFFWGLGSVKTFLNNIFIMSFEWPGLHAAIAKTAPIVKADAPYAAKFTFNLI
SAGGTAILFAGLLSVPVMPGYGYGRAFGCLARTCYQLRFPILTIVMILGLAQLMNYSGMS
STLGIAFTHTGALFPFFAPIMGWLGVFLTGSNTSSNALFGSMQHATASAVGVDPYLTVAA
NATGGVTGKMISPQSISVATASTHTVGQEGALFRFALKHSIAMTLVICVLVTLQAYVIPW
MLPAR