Protein Info for DVU1992 in Desulfovibrio vulgaris Hildenborough JW710

Name: cat
Annotation: antibiotic acetyltransferase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 PF00132: Hexapep" amino acids 111 to 145 (35 residues), 38.5 bits, see alignment 3.1e-14

Best Hits

Swiss-Prot: 73% identical to CAT4_MORMO: Chloramphenicol acetyltransferase (cat) from Morganella morganii

KEGG orthology group: K00638, chloramphenicol O-acetyltransferase [EC: 2.3.1.28] (inferred from 100% identity to dvu:DVU1992)

Predicted SEED Role

"Chloramphenicol acetyltransferase (EC 2.3.1.28)" (EC 2.3.1.28)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.28

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72AK0 at UniProt or InterPro

Protein Sequence (214 amino acids)

>DVU1992 antibiotic acetyltransferase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSDSPFRSPFEGIPLSQQVTNPNIRVGRFSYYSGYYHGHGFDDCARYLAPDRDDVDRLVI
GSFCSIGSGASFIMAGNQGHQLEWAATFPFFYMQDEAAFSGAVDGFVRAGDTLVGNDVWI
GTEAMIMPGVSIGDGAVIGSRALVTRDVEPYSIVGGNPAKFIRKRFDEENIALLLEMQWW
DWPLERLHEAMPLLCASRIRDLHTYWRGWCDTTR