Protein Info for DVU1987 in Desulfovibrio vulgaris Hildenborough JW710

Name: uvrA
Annotation: excinuclease ABC, A subunit (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 956 TIGR00630: excinuclease ABC subunit A" amino acids 6 to 935 (930 residues), 1237.9 bits, see alignment E=0 PF17760: UvrA_inter" amino acids 134 to 238 (105 residues), 127.2 bits, see alignment E=8.6e-41 PF17755: UvrA_DNA-bind" amino acids 290 to 354 (65 residues), 32.6 bits, see alignment 3e-11

Best Hits

KEGG orthology group: K03701, excinuclease ABC subunit A (inferred from 100% identity to dvl:Dvul_1185)

Predicted SEED Role

"Excinuclease ABC subunit A" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72AK5 at UniProt or InterPro

Protein Sequence (956 amino acids)

>DVU1987 excinuclease ABC, A subunit (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MSKHCIHIEGARQHNLKNVDIDIPRDELVVVCGPSGSGKSTLAFDIVYAEGQRRYVESLS
AYARQFLPQMDKPAVDKIEGLSPAISLEQQTSTRNPRSTVGTVTEVYDFLRVFYARLGRM
YCPQCGRPIEARAADEIIADILALGEGTRCIIMAPLVEHQKGTHADRFKKLKAEGFVRVR
VNGETTTIDDVPPLDKNRKHCIDLVVDRIVVKEGIRGRLADSVELALRYGNGRLVVEVPG
QGETVHSTESVCPSCRISLPAPSPQLFSFNSPQGACPHCSGLGSVDYFEPALLAPNRGLS
LNTGALLPWKNPRVFARWQADLEKLAKRFGVTLSTPLSAWPAAGLEVLFHGDGSLPHAAA
GDEGSGGGADTRKKGRRGADEAFGPPTGWSGVTQLLESGMQYGDAWRDEMSRYRQSRPCP
ACHGARLRPEALSVRVDDLDIHSFCSLSVARALAWLRERSFDGRHTLVAEPLLKELTHRL
EFMVNVGLDYISLGRNMSTLSGGEAQRIRLASQLGSGLVGVTYVLDEPSIGLHPRDNERL
IRTLRRLQQRGNTVLVVEHDEATIREADTVIELGPGSGALGGEVVFSGRVPDLLGTADTL
TARYLRGEMTIPLPESRRKGDGALTLRGVTTNNLQGLDCSIPFGVLTCVTGVSGSGKSSL
VVDTLYKHVALARGIKVDSPGSIGGIDGLDRIERIVAIDQTPIGRTPRSNPATYTKIFDE
IRDIFAMTADARKRGYKPGRFSFNVRGGRCEACGGDGQLRVEMHFLPDVFVTCDVCKGRR
YNHETLEVRYKGLNIAEVLDLTVRQARQFFENYPVLERRLGVLEDVGLEYLRLGQPATTL
SGGEAQRIKISRELGKRSLPGTLYILDEPTTGLHMHEVGKLIRVLHQLVDRGATVVVIEH
NTDVILSSDHVIDLGPGGGENGGRIVSAGTPEEIIADSASVTGAFLVQERAIRNGG