Protein Info for DVU1836 in Desulfovibrio vulgaris Hildenborough JW710
Name: cca
Annotation: tRNA nucleotidyltransferase, putative (TIGR)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00974, tRNA nucleotidyltransferase (CCA-adding enzyme) [EC: 2.7.7.72 3.1.3.- 3.1.4.-] (inferred from 100% identity to dvu:DVU1836)Predicted SEED Role
"tRNA nucleotidyltransferase (EC 2.7.7.21) (EC 2.7.7.25)" in subsystem Polyadenylation bacterial or tRNA nucleotidyltransferase (EC 2.7.7.21, EC 2.7.7.25)
KEGG Metabolic Maps
- Aminosugars metabolism
- Ascorbate and aldarate metabolism
- Ether lipid metabolism
- Fructose and mannose metabolism
- Lipopolysaccharide biosynthesis
- Nicotinate and nicotinamide metabolism
- Riboflavin metabolism
- Sphingolipid metabolism
- Thiamine metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.7.7.25, 2.7.7.72, 3.1.3.-, 3.1.4.-
Use Curated BLAST to search for 2.7.7.21 or 2.7.7.25 or 2.7.7.72 or 3.1.3.- or 3.1.4.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q72B04 at UniProt or InterPro
Protein Sequence (383 amino acids)
>DVU1836 tRNA nucleotidyltransferase, putative (TIGR) (Desulfovibrio vulgaris Hildenborough JW710) MKTYLVGGAVRDILIGRTPREHDIAFEASVAHFLQANPSARKVGKRIDVYLIGNVEHRPV QGGDIRADLLQRDFTINALALEADGTLHAHPDALADLRASIIRPASPGALMADPVRVLRA ARFAAQLPEMSLAQETLEAMRAVAAAGYLAEMPCEQVCRETLKALGSPAPERFFISLAKG GCLQPWFAEVADLTGVPAGPPAYHTGSAFDHTIDIMRRLAGDAFDVWLGLCHDLGKGTTP ADILPRHLGHEHRGEEAATALGQRLGMSNRFIRGGALAARMHMKAGRYDTLRPHTRVDLL LVLHHAGIIRNVWNLVTADSGIDHTATAMAELETILAVKLPPSLRGKGPESGRMLREMQC MALAARRTEPDGASGERCPGGPA