Protein Info for DVU1655 in Desulfovibrio vulgaris Hildenborough JW710
Name: aspC4
Annotation: aminotransferase, classes I and II (TIGR)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to DAPAT_DESVH: LL-diaminopimelate aminotransferase (dapL) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
KEGG orthology group: K10206, LL-diaminopimelate aminotransferase [EC: 2.6.1.83] (inferred from 100% identity to dvl:Dvul_1431)MetaCyc: 42% identical to glutamate--pyruvate aminotransferase AlaC (Escherichia coli K-12 substr. MG1655)
Alanine transaminase. [EC: 2.6.1.2]
Predicted SEED Role
"LL-diaminopimelate aminotransferase (EC 2.6.1.83), predicted alternative" (EC 2.6.1.83)
MetaCyc Pathways
- superpathway of L-lysine, L-threonine and L-methionine biosynthesis II (13/15 steps found)
- L-lysine biosynthesis VI (7/7 steps found)
- pyruvate fermentation to acetate and alanine (3/3 steps found)
- L-alanine degradation V (oxidative Stickland reaction) (2/2 steps found)
- L-alanine biosynthesis II (1/1 steps found)
- L-alanine degradation III (1/1 steps found)
- superpathway of L-alanine biosynthesis (3/4 steps found)
- anaerobic energy metabolism (invertebrates, cytosol) (4/7 steps found)
- L-alanine degradation II (to D-lactate) (1/3 steps found)
- superpathway of L-alanine fermentation (Stickland reaction) (4/9 steps found)
- L-alanine degradation VI (reductive Stickland reaction) (1/6 steps found)
- C4 photosynthetic carbon assimilation cycle, NAD-ME type (4/11 steps found)
- C4 photosynthetic carbon assimilation cycle, PEPCK type (6/14 steps found)
- superpathway of anaerobic energy metabolism (invertebrates) (6/17 steps found)
- Methanobacterium thermoautotrophicum biosynthetic metabolism (22/56 steps found)
KEGG Metabolic Maps
- Alanine and aspartate metabolism
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Carbon fixation in photosynthetic organisms
- Glutamate metabolism
- Lysine biosynthesis
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.6.1.2 or 2.6.1.83
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See Q72BI1 at UniProt or InterPro
Protein Sequence (388 amino acids)
>DVU1655 aminotransferase, classes I and II (TIGR) (Desulfovibrio vulgaris Hildenborough JW710) MAAFKLADRLATLPPYLFAGIDKVKAEVAARGVDIISLGIGDPDMATPGFIIEAMKEAIA RPANHQYPSYVGMLAFRQEVANWYDRRFGVSLDPATEVIGLIGSKEGIAHFPFAFINPGD LVLVCTPNYPVYHIATGFAGGEVQFVPLLEENDFLPDLDAIPEDTWKRAKMIFVNYPNNP TAATAPLGFYEKLVDICRRFDVIIAHDTAYTEIYYDEDNRPPSILSVPGAKDVAIEFHSL SKTYNMTGWRVGMAVGNPTLVAGLGKIKENMDSGIFQAVQEASIVALRDGDDFCRELRGI YRQRRDTVINALHKAGIQCRVPQATFYVWARVPQGHTSADFVTRVLQETGVVVTPGNGFG TPGEGFFRISLTVDNARLEEAVSRIAKL