Protein Info for DVU1595 in Desulfovibrio vulgaris Hildenborough JW710

Name: cheR-1
Annotation: chemotaxis protein methyltransferase (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 291 PF03705: CheR_N" amino acids 26 to 74 (49 residues), 52.6 bits, see alignment 6e-18 PF01739: CheR" amino acids 92 to 277 (186 residues), 210.6 bits, see alignment E=3.2e-66

Best Hits

Swiss-Prot: 36% identical to CHER_RHIEC: Probable chemotaxis protein methyltransferase (cheRch1) from Rhizobium etli (strain CFN 42 / ATCC 51251)

KEGG orthology group: K00575, chemotaxis protein methyltransferase CheR [EC: 2.1.1.80] (inferred from 100% identity to dvl:Dvul_1539)

Predicted SEED Role

"Chemotaxis protein methyltransferase CheR (EC 2.1.1.80)" in subsystem Bacterial Chemotaxis (EC 2.1.1.80)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.80

Use Curated BLAST to search for 2.1.1.80

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72BN9 at UniProt or InterPro

Protein Sequence (291 amino acids)

>DVU1595 chemotaxis protein methyltransferase (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MIQGPPERGGGDGAPFRPKSMTPKVFERMSRYVYEQVGIKLTPAKRIMLEARLQKRLRTL
GFDSYEQYAEYLFTARGQQEELQQFIDVVTTNTTEFFREGRHFELLAQKVLPRWRSQFGT
SRAMQIWSAGCSFGMEPYTLAMVLADFAERNSGFVFSVLATDISARALQHAQRGIYDEER
VESIPESFRKRFLLRSRERARKLVRIAPEIRHLVTFQRLNFMEDFSFRTPMDVIFCRNVI
IYFDKPTQERLFSRFCESLRPGGYLFIGHSESLTGMSLPLEAQAPTVYRKV