Protein Info for DVU1584 in Desulfovibrio vulgaris Hildenborough JW710

Name: rpoH
Annotation: sigma 70 family protein (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 PF00140: Sigma70_r1_2" amino acids 75 to 104 (30 residues), 48.9 bits, see alignment (E = 7.6e-17) TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 113 to 342 (230 residues), 102.3 bits, see alignment E=1.1e-33 PF04542: Sigma70_r2" amino acids 114 to 184 (71 residues), 62.5 bits, see alignment E=4e-21 PF04545: Sigma70_r4" amino acids 291 to 339 (49 residues), 47.5 bits, see alignment 1.5e-16

Best Hits

KEGG orthology group: K03089, RNA polymerase sigma-32 factor (inferred from 100% identity to dvl:Dvul_1549)

Predicted SEED Role

"RNA polymerase sigma factor RpoH" in subsystem Heat shock dnaK gene cluster extended or Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72BQ0 at UniProt or InterPro

Protein Sequence (356 amino acids)

>DVU1584 sigma 70 family protein (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MTKRPKAQHEDIADEKHVTVVDDVEIIDGPDDSADDTEDTEDFVDEDDVIDIGDDDHAPD
TFHLNAPATVSTGKDSLHLYLREISRFPMLKPEEEYELAKRVRETGDGDAAFRLVSSHLR
LVVKIAMDFQRRWMQNVLDLIQEGNVGLMRAVNKFDPEKGIKFSYYAAFWIKAYILKFIM
DNWRMVKIGTTQAQRKLFYNLNKERQKLILQGYDPDAATLSERLNVTKEQVVEMEQRLDA
SDVSLDIPVGDEGGGASRMDFLPALGPGIEDALSNHEIASMVQNRLQSIIPKLSDKEVDI
LQNRLLSEEPVTLREIGEKYDITRERVRQIEARLLQKIRDHLFKEIKDFSSDWINQ