Protein Info for DVU1323 in Desulfovibrio vulgaris Hildenborough JW710

Name: secY
Annotation: preprotein translocase, SecY subunit (TIGR)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 19 to 38 (20 residues), see Phobius details amino acids 71 to 94 (24 residues), see Phobius details amino acids 116 to 136 (21 residues), see Phobius details amino acids 153 to 173 (21 residues), see Phobius details amino acids 185 to 203 (19 residues), see Phobius details amino acids 215 to 236 (22 residues), see Phobius details amino acids 271 to 292 (22 residues), see Phobius details amino acids 312 to 332 (21 residues), see Phobius details amino acids 368 to 388 (21 residues), see Phobius details amino acids 394 to 412 (19 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 16 to 424 (409 residues), 423.9 bits, see alignment E=3.2e-131 PF00344: SecY" amino acids 72 to 412 (341 residues), 390.2 bits, see alignment E=3.7e-121

Best Hits

Swiss-Prot: 48% identical to SECY_AQUAE: Protein translocase subunit SecY (secY) from Aquifex aeolicus (strain VF5)

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 100% identity to dvl:Dvul_1745)

MetaCyc: 50% identical to Sec translocon subunit SecY (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q72CG0 at UniProt or InterPro

Protein Sequence (437 amino acids)

>DVU1323 preprotein translocase, SecY subunit (TIGR) (Desulfovibrio vulgaris Hildenborough JW710)
MALSGVDNLARLPELRSKLMWTFLLLAAYRIGVHVPIPGVDSSALADFFASVQNTLFGLF
DMFSGGGLRNLSVFALGIMPYISASIILQLLQVVSPDLKRLAKEEGAAGKRKLTQYTRYA
TVLITVIQGLGIAIGLESMHSPAGAPVVLEAGWAFRLVTIITLTAGTVLIMWLGEQITEK
GLGNGISLIIFSGIVAGIPGGILKSAQLISAGDMSLFAAIVILALMGLVLAGIVFVERAQ
RRIPIHYAKRQVGRKMFGGQTTHLPLRVNTAGVIPPIFASSLLLFPATVANFATSDWLKS
VASWFSPHTIPYNILFIALIVFFSFFYTAIIFDPKDIAENLKKGGGFIPGIRPGDKTKEY
IDKVLTRITLWGAIYISVISVLPMFLIAQFNVPFYFGGTSLLILVGVAMDFMSQIESHLI
SRQYEGLMNKTRIKGQR